Table 2.
Multivariate analysis of phosphatemia according to log-transformed ACR, stratified by mGFR
| Variable | mGFR<45 ml/min per 1.73 m2 | mGFR≥45 ml/min per 1.73 m2 | ||
|---|---|---|---|---|
| Regression coefficient | P Value | Regression coefficient | P Value | |
| All patients | n=1092 | n=646 | ||
| Model 0 | 0.0325±0.0036 | <0.001 | 0.0061±0.0038 | 0.1 |
| Model 1 | 0.0120±0.0035 | 0.001 | 0.0053±0.0035 | 0.1 |
| Patients with FGF-23 | n=285 | n=112 | ||
| Model 0 | 0.0317±0.0069 | <0.001 | −0.0051±0.0082 | 0.5 |
| Model 1 | 0.0180±0.0068 | 0.01 | −0.0058±0.0076 | 0.4 |
| Model 2 | 0.0130±0.0059 | 0.03 | −0.0060±0.0075 | 0.4 |
Estimated regression coefficient (β±SD, P value). Model 0: crude model. Model 1: adjustments for sex, sub-Saharan origin, diabetes, age, body mass index, mGFR, mean BP, log-1,25(OH)D, ferritin, fractional excretion of phosphate, center, log-PTH, and 24-hour protein intake. Model 2: model 1 plus FGF-23.