Table 2.
Adjusted RH for progression to ESRD for low, middle, and high tertiles of estimated DAL in NHANES III participants
| Model Adjustment | Low | MDRD Equation RH (95% CI) | CKD-EPI Equation RH (95% CI) | ||||||
|---|---|---|---|---|---|---|---|---|---|
| n | Middle | High | P Trend | n | Middle | High | P Trend | ||
| Demographic factors | 1.00 (ref) | 1486 | 2.16 (1.06 to 4.42) | 4.13 (2.09 to 7.81) | 0.03 | 1332 | 3.10 (1.79 to 6.95) | 6.10 (3.10 to 9.31) | 0.008 |
| +Nutritional factors | 1.00 (ref) | 1251 | 2.09 (1.01 to 4.32) | 3.45 (1.83 to 6.52) | 0.04 | 1130 | 2.81 (1.23 to 6.36) | 4.45 (2.23 to 8.89) | 0.03 |
| +Clinical factors | 1.00 (ref) | 1251 | 1.59 (0.78 to 3.25) | 2.73 (1.44 to 5.18) | 0.06 | 1130 | 1.53 (1.02 to 2.29) | 2.75 (1.51 to 5.01) | 0.04 |
| +Kidney function/damage status | 1.00 (ref) | 1195 | 1.81 (0.89 to 3.68) | 3.04 (1.58 to 5.86) | 0.05 | 1081 | 1.62 (1.06 to 2.48) | 3.14 (1.70 to 5.82) | 0.01 |
Demographic factors are age, sex, and race. Nutritional factors are BSA, total caloric intake per day, serum bicarbonate, and protein intake. Clinical factors are diabetes and hypertension. Kidney function/damage status includes eGFR and albuminuria. ref, Reference.