Supplementary Table 1. Baseline characteristics according to insulin sensitivity (kitt%).
| Characteristic | Men | Women | ||||||
|---|---|---|---|---|---|---|---|---|
| Low tertile | Middle tertile | High tertile | P value | Low tertile | Middle tertile | High tertile | P value | |
| Age, yr | 56.84±11.72 | 56.76±10.99 | 55.01±10.54a,b | <0.001 | 60.22±9.92 | 60.30±9.31 | 58.67±9.54a,b | <0.001 |
| DM duration, yr | 8.39±7.63 | 7.36±7.05a | 6.38±6.62a,b | <0.001 | 9.02±6.76 | 7.57±6.70a | 6.48±6.42a,b | <0.001 |
| Body mass index, kg/m2 | 24.69±3.35 | 24.54±3.35 | 24.34±3.16 | 0.071 | 24.58±3.28 | 24.63±3.26 | 24.76±3.59 | 0.52 |
| Waist circumference, cm | 89.25±7.85 | 87.59±7.17a | 85.05±7.12a,b | <0.001 | 83.64±8.15 | 81.87±7.50a | 79.48±8.10a,b | <0.001 |
| Kitt, %/min | 1.04±0.29 | 1.86±0.23a | 3.08±0.64a,b | <0.001 | 1.06±0.29 | 1.86±0.22a | 3.04±0.68a,b | <0.001 |
| Fasting glucose, mg/dL | 184.82±65.57 | 153.65±50.30a | 137.87±41.19a,b | <0.001 | 184.28±64.10 | 149.74±50.52a | 134.65±43.01a,b | <0.001 |
| C-peptide, ng/mL | 2.35±0.92 | 2.08±0.73a | 1.88±0.75a,b | <0.001 | 2.29±0.98 | 2.03±0.78a | 1.77±0.67a,b | <0.001 |
| HbA1c, % | 9.07±2.02 | 8.17±1.74a | 7.75±1.70a,b | <0.001 | 9.10±1.83 | 8.20±1.69a | 7.63±1.45a,b | <0.001 |
| Total cholesterol, mg/dL | 198.39±44.22 | 193.35±37.21a | 186.56±37.91a,b | <0.001 | 209.65±44.00 | 204.43±40.82a | 199.37±39.44a,b | <0.001 |
| Triglyceride, mg/dL | 189.50±143.78 | 161.09±109.20a | 134.80±83.53a,b | <0.001 | 184.68±119.44 | 155.30±93.79a | 128.25±77.02a,b | <0.001 |
| HDL-C, mg/dL | 46.42±12.25 | 46.75±11.72 | 48.27±12.17a,b | 0.001 | 49.39±12.16 | 51.34±13.24a | 52.32±13.07a | <0.001 |
| LDL-C, mg/dL | 115.53±36.53 | 113.63±31.09 | 109.77±31.34a | 0.001 | 122.74±36.71 | 120.26±35.54 | 118.92±33.72 | 0.09 |
| VFT, mm | 54.36±18.66 | 50.50±17.19a | 45.25±16.13a,b | <0.001 | 46.81±17.86 | 43.05±16.46a | 37.24±15.39a,b | <0.001 |
| CIMT, mm | 0.857±0.205 | 0.850±0.186 | 0.823±0.184a,b | <0.001 | 0.824±0.185 | 0.807±0.171 | 0.794±0.178a | 0.001 |
| MetS componentsc | ||||||||
| Hypertriglyceridemia | 641 (57.4) | 560 (50.0) | 408 (36.7) | <0.001 | 670 (64.4) | 540 (51.9) | 404 (38.9) | <0.001 |
| Low HDL-C | 306 (27.6) | 279 (25.1) | 238 (21.6) | 0.004 | 568 (55.0) | 530 (51.6) | 478 (47.0) | 0.001 |
| Hypertension | 871 (79.4) | 836 (75.5) | 760 (69.7) | <0.001 | 801 (77.7) | 770 (75.8) | 711 (70.1) | <0.001 |
| More than 2 factors | 623 (56.7) | 539 (48.8) | 414 (37.8) | <0.001 | 730 (71.1) | 639 (62.8) | 510 (50.7) | <0.001 |
Values are presented as mean±standard deviation or number (%).
DM, diabetes mellitus; HbA1c, glycosylated hemoglobin; HDL-C, high density lipoprotein cholesterol; LDL-C, low density lipoprotein cholesterol; VFT, visceral fat thickness; CIMT, carotid intima-media thickness; MetS, metabolic syndrome.
aP<0.05 vs. low tertile, bP<0.05 vs. middle tertile, cHypertriglyceridemia, triglycerides ≥150 mg/dL or taking medication; low HDL-C, <40 mg/dL for men and <50 mg/dL for women; hypertension, blood pressure ≥130/85 mm Hg or taking antihypertensive medication.