Figure 7.

Fucoidan inhibits the cell metastasis in vivo. Popliteal, inguinal and axillary lymph nodes were removed and photographed (A); shown with their average weight, respectively (B); axillary lymph nodes with H.E staining (C); the relative metastasis rate (D). Note that the tissue structures of the metastatic lymph node were obscured in the control; however, the structure of the lymph node tissue was obvious in mice treated with fucoidan. Data are the mean ± SD. * p < 0.05, ** p < 0.01, compared with the normal saline (NS) group.