Table 2.
Pathogenic Strain | E5 | CIP1 | P1 | TE10 | CN10 | Extract E3 (4 mg/mL) |
---|---|---|---|---|---|---|
S. aureus ATCC 29213 | (−) | 19 mm | 9 mm | 22 mm | 16 mm | 11 mm |
S. aureus NCTC 12981 (ATCC 25923) | 19 mm | (−) | 11 mm | (−) | 16 mm | 11.5 mm |
S. aureus MRSA ATCC 33593 | (−) | 19 mm | (−) | (−) | 8 mm | 13.5 mm |
S. aureus MRSA NCTC 10442 | (−) | 18 mm | (−) | (−) | 16 mm | 13 mm |
S. aureus MRSA ATCC 43300 | (−) | 16 mm | 8 mm | 18 mm | 9 mm | 10.5 mm |
S. epidermidis ATCC 35982 | (−) | 26 mm | (−) | 22 mm | 14 mm | 13.5 mm |
S. epidermidis NCTC 13360 (ATCC 12228) | 21 mm | 22 mm | (−) | (−) | 20 mm | 12 mm |
S. epidermidis MRSE NCTC 11964 | 11 mm | (−) | (−) | (−) | (−) | 7 mm |
S. haemolyticus NCTC 11042 | 18 mm | 20 mm | (−) | (−) | 16 mm | 13.5 mm |
S. hominis NCTC 11320 | 27 mm | 25 mm | 26 mm | (−) | 26 mm | 10 mm |
S. pyogenes NCTC 8306 (ATCC 12204) | (−) | 26 mm | (−) | 20 mm | 15 mm | 15 mm |
S. agalactiae NCTC 8542 | 20 mm | 15 mm | 11 mm | 21 mm | 17 mm | 13 mm |
P. mirabilis ATCC 7002 | (−) | 26 mm | (−) | (−) | 16 mm | 6 mm |
P. aeruginosa PAO1 | (−) | 19 mm | (−) | (−) | 18 mm | 0 mm |
S. maltophilia NCTC 10257 (ATCC 13637) | (−) | 30 mm | (−) | 16 mm | 20 mm | 10 mm |
E. coli NCTC 12241 | 18 mm | 14 mm | 11 mm | 27 mm | 19 mm | 10 mm |
C. violaceum ATCC 12472 | 20 mm | 32 mm | (−) | 25 mm | 20 mm | 12 mm |
C. albicans | n.a. | n.a. | n.a. | n.a. | n.a. | 0 mm |
Antimicrobial activity of Halidrys siliquosa extract E3. Zones of inhibition (mm) using the disc diffusion assays. Control antibiotics: Erythromycin 5 µg (E5), Penicillin 1 Unit (P1), Tetracycline 10 µg (TE10), Ciprofloxacin 5 µg (CIP1) and Gentamycin 10 µg (CN10). Disc diffusion using 100 µL of MeOH extract at 4 mg/mL. (−) = no. activity detected, n.a. = not tested (yeast).