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. 2015 Jun 15;142(12):2147–2162. doi: 10.1242/dev.121046

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© 2015. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 8. — Rab8a facilitates anterograde transport of Gpr177-Wnt. Rab8a facilitates the transport of post-Golgi Gpr177-Wnt vesicles to the plasma membrane for secretion. Loss of Rab8a attenuates Gpr177 exocytotic traffic and, via an unknown mechanism (red dotted arrows), may reroute Gpr177 into endolysosomes. TGN, trans-Golgi network.