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. 2015 Apr 15;8(4):6446–6455.

Figure 4.

Figure 4

ERK5 modulation of cytarabine-induced cell death in HL-60 cells. HL-60-siERK5 or HL-60-siControl cells exposed to cytarabine (3.75- and 7.5-μg/ml) for 0, 12, 24, 36, and 48 h or cytarabine (3.75 μg/ml) for 24 h. A, B. MTT assay.*P < 0.05, **P < 0.01. C, D. ELISA assay (representative experiments); E. HL-60-siERK5 or HL-60-siControl cells were exposed to 3.75 μg/ml concentrations of cytarabine at 37°C in a humidified incubator for 14 days. Cell colonies were counted under a microscope using three different plates. *P < 0.05, **P < 0.01.