Figure 3.

GO terms that are associated with coding gene functions of (A-C) up-regulated lncRNAs and (D-F) down-regulated lncRNAs. GO analysis is a functional analysis associating differentially expressed mRNAs with GO categories. GO categories were derived from Gene Ontology (www.geneontology.org), which comprised three structured networks of defined terms that described gene product attributes. P values denoted the significance of GO term enrichment in the differentially expressed mRNA list. The smaller the P values were, the more significant the GO term was (P value ≤ 0.05 was recommended).