Table 3.
Side effects of triple therapy group vs. triple therapy with probiotics group
| Side Effects | The incidence in the triple therapy group | The incidence in the triple therapy with probiotics group | OR | 95% CI | P value |
|---|---|---|---|---|---|
| nausea | 136/1374 (11.86%: 95% CI = 12.31%-25.39%) | 97/1385 (7%: 95% CI = 6.53%-14.15%) | 1.97 | 1.50-2.61 | 0.000 |
| diarrhea | 224/1523 (14.71%: 95% CI = 15.84%-26.80%) | 97/1531 (6.34%: 95% CI = 5.07%-10.50%) | 2.69 | 2.09-3.47 | 0.000 |
| epigastric pain | 84/719 (11.68%: 95% CI=9.48%-34.20%) | 63/712 (8.85%: 95% CI = 6.22%-25.12%) | 1.54 | 1.04-2.28 | 0.030 |
| vomiting | 46/640 (7.19%: 95% CI = 5.12%-17.36%) | 16/648 (2.47%: 95% CI = 1.59%-3.87%) | 2.84 | 1.66-4.86 | 0.000 |
| taste distortion | 183/989 (18.50%: 95% CI = 19.84%-46.43%) | 123/1003 (12.26%: 95% CI = 6.18%-31.83%) | 2.13 | 1.58-2.87 | 0.000 |
| loss of appetit | 46/305 (15.08%: 95% CI = 11.76%-17.68%) | 51/320 (15.94%: 95% CI = 2.34%-28.73%) | 0.94 | 0.61-1.45 | 0.786 |
| bloating | 142/411 (34.55%: 95% CI = 12.09%-51.53%) | 84/416 (20.19%: 95% CI = 7.50%-31.96%) | 2.17 | 1.57-3.01 | 0.000 |
| constipation | 46/644 (7.14%: 95% CI = 5.97%-17.08%) | 27/638 (4.23%: 95% CI = 3.41%-12.96%) | 1.84 | 1.12-3.04 | 0.016 |
| skin rash | 35/304 (11.51%: 5% CI = -4.30%-31.28%) | 12/316 (3.8%: 95% CI = 1.84%-5.21%) | 3.01 | 1.61-5.64 | 0.001 |