Table 3.

Comparison of spine fracture events between BP group and BP+PPI group

Study	BP		BP+PPI
	Events	Total	Events	Total
Itoh [6]	2	86	2	94
Roux [15]	1414	2489	146	240
Abrahamsen1 [12]	45	13116	29	4089
Abrahamsen2 [12]	80	14795	63	6088

BP, bisphosphonate; PPI, proton pump inhibitors.