Table 1.
Characteristics of the studies included on RAD51 G135C polymorphism
| First author | Year | Country | Ethnicity | Source of control | Genotyping method | Case | Control | HWE | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
| ||||||||||||
| GG | GC | CC | GG | GC | CC | |||||||
| Lu | 2007 | USA | Caucasian | HCC | PCR- RFLP | 624 | 91 | 1 | 622 | 96 | 1 | 0.17 |
| Werbrouck | 2008 | Belgium | Caucasian | HCC | PCR | 136 | 15 | 1 | 134 | 23 | 0 | 0.322 |
| Sliwinski | 2010 | Poland | Caucasian | HCC | PCR- RFLP | 101 | 88 | 2 | 258 | 64 | 32 | < 0.001 |
| Gresner | 2012 | Poland | Caucasian | PCC | PCR | 67 | 13 | 1 | 71 | 14 | 2 | 0.217 |
| Romanowicz-Makowska | 2012 | Poland | Caucasian | PCC | PCR-RFLP | 174 | 69 | 10 | 190 | 58 | 5 | 0.816 |
| Kayani | 2014 | Pakistan | Asian | HCC | PCR-RFLP | 120 | 70 | 10 | 106 | 41 | 3 | 0.674 |
HWE: Hardy-Weinberg equilibrium; HCC: hospital-based case-control; PCC: population-based case-control; PCR: polymerase chain reaction; RFLP: restriction fragment length polymorphism.