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Effects of honokiol on tumor suppressors and apoptosis-related proteins. Human gastric carcinoma cells were treated with vehicle or honokol (5 or 10 μM) for 48 h, and the expression levels of p53 and p21 were determined by western blotting and densitometric analyses (A). The expression levels of BAX and Bcl-2 were determined by western blotting and densitometric analyses (B). Values are expressed as mean ± SEM, n = 3 in each group. *P < 0.05, **P < 0.01 versus control group.
