Table 3.
Summary table of the subgroup meta analysis results
| Analysis | N | Hazard ratio risk (95% CI) | Heterogeneity P value | I2 (%) |
|---|---|---|---|---|
| All studies | 12 | 1.74 (1.39-2.19) | < 0.001 | 82.4 |
| Geographical area | ||||
| Eastern countries | 7 | 1.97 (1.34-2.88) | < 0.001 | 87.8 |
| Western countries | 5 | 1.38 (1.22-1.56) | 0.122 | 45 |
| Cut-off value | ||||
| Value ≥ 400 × 109/L | 6 | 2.19 (1.18-4.06) | < 0.001 | 92.4 |
| Value < 400 × 109/L | 6 | 1.44 (1.25-1.67) | 0.139 | 36.3 |
| Sample size | ||||
| Sample size ≥ 300 | 7 | 1.35 (1.23-1.49) | 0.693 | 0 |
| Sample size < 300 | 5 | 2.81 (1.81-4.35) | 0.017 | 67 |