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. 2015 Jun 29;9:85. doi: 10.3389/fnana.2015.00085

FIGURE 5.

FIGURE 5

Schema of the progression of hippocampal neurogenesis in adult marmosets. The figure, adapted from Song et al. (2013), takes into account only markers used in the present study. In adult marmosets, around 66% of the replication competent MCM2+ cell co-label with Ki67. MCM2 expression extends until later stages, as 6% of the MCM2+ cells co-express DCX. Of all proliferating Ki67+ cells, around 30% can be assigned to the early intermediate precursor stage when cells express Tbr2. Proliferation at the stage of DCX+ young neurons is almost absent. The transition between Tbr2 and DCX was not examined in this study. The population size of DCX+ and CR+ cells are on average four times larger than those of MCM2, Ki67 or Tbr2, with minimal (0.4%) overlap between DCX+ and CR+ stages. CR+ cells therefore represent a distinct, prominent young neuron population.