Table 2.
Estimated cell numbers in neurogenesis.
| Animal | Sex | Age | MCM2+ ∗ | Ki67+ ∗ | Tbr2+ | DCX+ ∗ | CR+ | MCM2+/Ki67+ | Tbr2+/Ki67+ | DCX+/Ki67+ | MCM2+/DCX+ | CR+/DCX+ | Apoptotic cell |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Marmoset | |||||||||||||
| C 05 s | F | 0 | 257080 | 94740 | 142720 | NA | NA | 97330 | 40960 | NA | NA | NA | NA |
| C 06 s | F | 0 | 224290 | 62050 | 76700 | NA | NA | 79880 | 20630 | NA | NA | NA | NA |
| C 09 s | M | 20 | 5050 | 5700 | 5360 | 21220 | 8300 | 4660 | 2240 | 0 | 120 | 80 | 156 |
| C 11 s | F | 20 | 8140 | 9830 | 9460 | 35400 | 8000 | 6500 | 3380 | 0 | 400 | 200 | 168 |
| C 01 | M | 31.25 | 1120 | 750 | 1060 | 7250 | 11180 | 700 | 80 | 0 | 20 | 100 | 150 |
| C 02 s | M | 32 | 1710 | 1300 | 2740 | 12780 | 11380 | 1040 | 560 | 20 | 60 | 40 | 186 |
| C 03 s | M | 32 | 1090 | 920 | 1180 | 8250 | 12780 | 680 | 200 | 0 | 60 | 20 | 210 |
| C 07 | M | 46.5 | 1190 | 760 | 840 | 2950 | 8360 | 600 | 180 | 0 | 100 | 0 | 60 |
| C 04 | M | 56.25 | 600 | 220 | 580 | 5730 | 7920 | 220 | 40 | 0 | 80 | 0 | 120 |
| C 10 | F | 63.5 | 1660 | 950 | 580 | 3780 | 5700 | 1240 | 280 | 0 | 180 | 40 | 60 |
| C 08 | M | 122.5 | 730 | 650 | 480 | 1830 | 5540 | 560 | 200 | 0 | 40 | 0 | 24 |
| Mouse | |||||||||||||
| C57BL/6 | M | 3.5 | NA | 5820 | NA | 14440 | NA | NA | NA | NA | NA | NA | NA |
Total estimated numbers of immunopositive cells in marmosets and mice. Marmosets are ordered according to age (in months), siblings are marked with ‘s’. Estimated total numbers are given for one hemisphere (unilateral) and rounded to the next 10. ∗Cell estimates are given as mean numbers of independently assessed quantification from different immunomarker combinations for Ki67 (four), DCX (three) and MCM2 (two). Calculated coefficient of error (CE) in marmoset was for Ki67: CE = 0.07 (0.03–0.12); DCX: CE = 0.06 (0.04–0.08); Apoptotic cells: 0.14 (0.08–0.34). In mice coefficient of error (CE) was for Ki67: CE = 0.06; and DCX: CE = 0.08. Data of mice represent means of 10 animals. NA, not assessed.