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Effects of 3dSB on intracellular FPP and GGPP levels. Cells were incubated in the presence of 3dSB or lovastatin (Lov) for 24 h in media containing either standard FCS (a) or LPDS (b). Intracellular FPP and GGPP levels were determined as described in the “Materials and methods” and are expressed as a percent of control (mean ± SD of three independent experiments). * Denotes p < 0.05 per unpaired two-tailed t test and compares the treated cells to the control untreated cells
