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. Author manuscript; available in PMC: 2015 Jun 29.
Published in final edited form as: Lipids. 2011 Jun 2;46(10):907–921. doi: 10.1007/s11745-011-3572-y

Fig. 5.

Fig. 5

Effect of 3dSB on FPP and GGPP levels in primary acute leukemia cells. Mononuclear cells were isolated from the peripheral blood of patients with newly diagnosed acute leukemia and incubated ex vivo with 3dSB or lovastatin for 24 h. All patients had greater than 40,000 K/mm3 circulating blasts. Formal pathological review of the patient bone marrow samples revealed acute myelomonocytic leukemia for patient 1, acute myeloid leukemia with t(11;17) translocation for patient 2, and acute myeloid leukemia with aberrant CD7 expression for patient 3