Table 2.
FPP (pmol/106 cells) (Mean ± SD) |
GGPP (pmol/106 cells) (Mean ± SD) |
|
---|---|---|
RPMI-8226, FCS | 0.168 ± 0.030 | 0.273 ± 0.022 |
RPMI-8226, LPDS | 0.122 ± 0.033 | 0.235 ± 0.096 |
U266, FCS | 1.87 ± 0.271 | 0.682 ± 0.193 |
U266, LPDS | 15.5 ± 1.25a | 1.115 ± 0.223 |
SF-295, FCS | 0.088 ± 0.002 | 0.367 ± 0.023 |
SF-295, LPDS | 0.155 ± 0.005a | 0.534 ± 0.032a |
A549, FCS | 0.146 ± 0.003 | 0.291 ± 0.031 |
A549, LPDS | 0.242 ± 0.026a | 0.460 ± 0.048a |
Cells were incubated for 24 h in media containing either standard FCS or LPDS. FPP and GGPP levels were measured as described in the section “Materials and methods”. The means and standard deviations of the results of three independent experiments are shown
p < 0.05 by two-tailed t testing comparing FCS to LPDS levels