Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Mar 25;6(13):10840–10852. doi: 10.18632/oncotarget.3450

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © 2015 Cheng et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

PMC Copyright notice

(A) Panc1 cells were transfected with siHOTTIP or siCtrl and gene expression was analyzed using HumanHT-12 v4 expression beadchip (Illumina Inc.) array, and (B) the effects of siHOTTIP on different pathways were determined by gene ontology enrichment analysis. (C) Overlap of common genes was observed after treatment of Panc1 cells with siHOTTIP or siHOTAIR. (D) Panc1 cells were transfected with siHOTTIP and GDF15 mRNA, and protein levels were determined compared to the effects of siHOTAIR. Results for GDF15 mRNA are means ± SD for 3 replicated determinations, and significant (p < 0.05) change is indicated (*). Cells were also transfected with siHOTTIP or siHOTAIR and GDF15 protein was analyzed by Western blots. The 1457 value for siHOTTIP (C) includes some genes detected by more than one probe (also see Figure 4A).