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. 2015 Mar 30;6(13):10964–10977. doi: 10.18632/oncotarget.3696

Figure 1. Overexpression of miR-942 is positively associated with ESCC prognosis.

Figure 1

(A) Expression profiling of miR-942 from the Cancer Genome Atlas (TCGA) datasets in primary esophageal tumours (T, n=177) and the adjacent normal tissues (ANT, n=13) (P = 0.002). (B-C) Real-time PCR analysis of miR-942 expression in 2 NEECs and 12 ESCC cell lines (B), as well as 10 paired ESCC samples (T) and adjacent normal tissues (ANT). Transcript levels were normalized by to U6 expression. Each bar represents the mean ± SD of three independent experiments. * P < 0.05. (D) Correlation of miR-942 expression in WHO grading of ESCC assessed by real-time PCR. Transcript levels were normalized by U6 expression. The boundaries of the boxes represent the lower and upper quartiles; lines within boxes and whiskers denote median and extremum, respectively. * P < 0.05 (E) Kaplan-Meier curves of ESCC patients with low- versus high-expression of miR-942 (n = 158; P <0.001, log-rank test).