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. 2015 Mar 14;6(13):11191–11202. doi: 10.18632/oncotarget.3586

Figure 2. Silencing of spinophilin increases cellular growth rates, migration and invasion.

Figure 2

(A) A significant increase (p<0.05) of cell growth has been observed in both cell lines with reduced spinophilin levels. Data are generated by three independent biological replicates with six technical replicates using the WST-1 assay. (B) The silencing of spinophilin in SUM159 cells promotes cell migration in the xCELLigence system compared to control cells as indicated by the increase of the cell index on the Y-axis. (C) The silencing of spinophilin in SUM159 cells also leads to an increased invasion in the xCELLigence system compared to control cells as indicated by the increase of the cell index. Plotted curves represent the averages from two independent wells/measurements and cells were monitored for 24 hours.