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. 2015 Mar 20;6(13):11492–11506. doi: 10.18632/oncotarget.3416

Figure 7. Effect of MACC1 on expression of VE-cadherin, VEGFR2, and E-cadherin.

Figure 7

Overexpression of MACC1 (oxMACC1) or silencing of MACC1 (shMACC1) altered the expression of VE-cadherin, VEGFR2, and E-cadherin mRNA (A) and protein (B) in BGC-823 cells. (C) VE-cadherin and VEGFR2 expression in BGC-823 cells were assessed by flow cytometry. *p < 0.05; **p < 0.01, n = 3 in each group. (D) VE-cadherin expression was increased in oxMACC1 xenograft GC tissues and decreased in shMACC1 tissues, **p < 0.01, n = 6 in each group. (E) VE-cadherin expression in human GC tissues with positive or negative immunostaining for MACC1. **p < 0.01, n = 73 and n = 15 for MACC1 positive or MACC1 negative, respectively.