Table 1. Patient characteristics.
Characteristics | N = 29 | % |
---|---|---|
Initial diagnosis | ||
Age | 57, 1 (37, 2–74, 1) | |
Gender (M / W) | 18M / 11W | 62% / 38% |
KPS (median) | 80 | |
60 | 1 | 4% |
70 | 11 | 38% |
80 | 14 | 48% |
90–100 | 3 | 10% |
MMS | ||
Normal | 22 | 85% |
Abnormal | 4 | 15% |
Steroids | 20 | 71% |
RPA classification | ||
III | 4 | 15% |
IV | 19 | 73% |
V–VI | 3 | 12% |
Type of surgery | ||
Gross total resection | 28 | 96% |
Other | 1 | 4% |
MGMT status | ||
Methylated / Unmethylated | 6 / 21 | 22% / 78% |
IDH 1/2 mutation | 0 | 0% |
First line treatment | ||
Radiotherapy and temozolomide | 27 | 93% |
Radiotherapy and BCNU | 2 | 7% |
Recurrence | ||
Age | 58 (38, 2–75, 7) | |
KPS (median) | 70 | |
60 | 6 | 21% |
70 | 15 | 52% |
80 | 7 | 24% |
90 | 1 | 3% |
Steroids | 24 | 86% |
Treatment at progression | ||
Gliadel | 29 | 100% |
Bevacizumab | 14 | 48% |
Total number of lines | ||
2 | 6 | 21% |
3 | 14 | 48% |
4 or 5 | 9 | 31% |
KPS: Karnofsky Performans Satus; MMS: MiniMental Status; RPA: Recursive Partitioning Analysis