Table 3.

Scales derived from the Twins and Early Development Study (TEDS) measures at 4 years applied to the children exposed to GM-CSF compared with control children in PROGRAMS trial groups at 5 years of age

		GM-CSF (n=62)		Control (n=54)
Outcome	Max score	No or median	% or IQR	No or median	% or IQR
Your child's development
Talking (1–6), median (IQR)		6	6, 6	6	6, 6
Actions or words—n% with actions		3/61	5%	3	6%
Sounds younger—n%		17	27%	8	15%
Your child's words (total n)	48	41	29, 46	41	33, 48
Using language (total ‘yes’ responses)	14	12	7, 13	13	11, 14
Books (total ‘yes’ responses)	12	8	6, 9	8	6, 9
Communication worries n (%)		23	37%	14	26%
Professional advice n (%)		32	52%	24	44%
Communication score, median (IQR)	30	26	22, 26	26	24, 27
Total ‘TEDS’ score, median (IQR)	94	85	66, 93	86	80, 93

GM-CSF, granulocyte macrophage colony stimulating factor.