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. 2013 Oct 9;77(2):133–140. doi: 10.1007/s12262-013-0984-3

Table 3.

The summary on results of meta-analysis and GRADE system

Outcome No. of studies HS CS Effect estimate Quality of evidence
Events Total Events Total RR/MD [95 % CI] p value
Anastomotic leakage 9 52 447 38 423 1.30 [0.87, 1.92] 0.20 ⊕⊕⊕⊖Moderatea
Anastomotic strictures 8 45 330 55 300 0.97 [0.47, 1.99] 0.93 ⊕⊕⊕⊖Moderatea
Postoperative mortality 6 15 275 18 272 0.83 [0.43, 1.58] 0.57 ⊕⊕⊕⊖Moderatea
Blood loss (ml) 3 207 206 39.68 [−6.97, 86.33] 0.10 ⊕⊕⊖⊖Lowa,b
Operative time (min) 4 239 237 18.05 [−3.22, 39.33] 0.10 ⊕⊕⊖⊖Lowa,b

aBecause of the nature of the surgery trials, it was difficult to perform blinding except blinding of the statistician; allocation concealment was unclear in 44.4 % of included studies

bSmall sample size and number of events provided. Additionally, the 95 % CI around the pooled effect was wide