Table 3.
The summary on results of meta-analysis and GRADE system
| Outcome | No. of studies | HS | CS | Effect estimate | Quality of evidence | |||
|---|---|---|---|---|---|---|---|---|
| Events | Total | Events | Total | RR/MD [95 % CI] | p value | |||
| Anastomotic leakage | 9 | 52 | 447 | 38 | 423 | 1.30 [0.87, 1.92] | 0.20 | ⊕⊕⊕⊖Moderatea |
| Anastomotic strictures | 8 | 45 | 330 | 55 | 300 | 0.97 [0.47, 1.99] | 0.93 | ⊕⊕⊕⊖Moderatea |
| Postoperative mortality | 6 | 15 | 275 | 18 | 272 | 0.83 [0.43, 1.58] | 0.57 | ⊕⊕⊕⊖Moderatea |
| Blood loss (ml) | 3 | – | 207 | – | 206 | 39.68 [−6.97, 86.33] | 0.10 | ⊕⊕⊖⊖Lowa,b |
| Operative time (min) | 4 | – | 239 | – | 237 | 18.05 [−3.22, 39.33] | 0.10 | ⊕⊕⊖⊖Lowa,b |
aBecause of the nature of the surgery trials, it was difficult to perform blinding except blinding of the statistician; allocation concealment was unclear in 44.4 % of included studies
bSmall sample size and number of events provided. Additionally, the 95 % CI around the pooled effect was wide