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. Author manuscript; available in PMC: 2015 Jun 29.
Published in final edited form as: Virology. 2006 Feb 28;348(2):462–474. doi: 10.1016/j.virol.2006.01.014

Table 4.

Steady state kinetics of single nucleotide incorporation

RTs Template-primer
RNA–DNA kcat (s−1) DNA–DNA kcat (s−1)
WT 0.060 ± 0.0192 0.019 ± 0.0300
K103N 0.049 ± 0.0223 0.042 ± 0.0065
G190A 0.035 ± 0.0038 0.046 ± 0.0208
G190S 0.021 ± 0.0148 0.023 ± 0.0111

P = 0.066 for K103N kcat vs. wt, DNA/DNA template, t test.

P > 0.10 for all other mutants and templates, compared to wild-type, t test.