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. 2015 Jun 10;17(1):155. doi: 10.1186/s13075-015-0666-6

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© Fernandes-Cerqueira et al. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — a. Percentage of responses among tested patients. Immune reactivity (%) against the respective peptide in sera from CCP2-positive patients. Positive immune reactivity (%) (dark grey) against each individual citrullinated fibrinogen peptide in sera from CCP2-positive patients; light gray represents negative immune response (%) against each individual citrullinated peptide in CCP2-positive sera tested. b. Relative frequency (%) of patient sera reacting to one, two, three, or four citrullinated fibrinogen peptides