Table 1.

Previously identified breast cancer survival genes in cancer-related pathways

Pathway	Nearest gene	References
DNA repair	XRCC1, XRCC2, XRCC3, RAD51B, LIG4, ERCC2	[6,28-32]
Cell cycle control	CCND1, CCND3, PRKAG2, TP53, SIPA1, FGFR2, PPP2R2B	[28,33-38]
Matrix metalloproteinases	MMP7, MMP8, MMP2, SERPINE1, TIMP-3	[23,40-44]
Immune and drug response, metabolism	Il-10, IL-6, IL-21, MPO, GSTP1, COMT, CYP19A1, CYP1A1, SULT1E1, NEF2L2, TLR4, SLC28A3, CD24, CD44, NQO1	[14,22,24,45-57]
Tumour progression	NOS3, VEGF, NME1, SELE, GNAS1, ZFP36, TGF	[58-64]
Vitamin D receptors	RXRA, VDR	[65,66]
Miscellaneous	TOX3, MTHFR, COX11, OCA2, PLAUR.	[4,7,34,65,67]

NB: the genes mentioned here are the candidate genes listed in the previous publications or are the nearest gene to the single nucleotide polymorphism (SNP) and are not necessarily the genes on which the SNPs have a functional effect.