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. Author manuscript; available in PMC: 2015 Jun 29.
Published in final edited form as: Curr Opin Genet Dev. 2014 Jan 28;25:38–42. doi: 10.1016/j.gde.2013.11.017

Figure 1.

Figure 1

eRNAs induce chromatin looping and transcriptional activation. Stimulus-induced expression of eRNAs cooperate with transcriptional cofactors such as Mediator and Cohesin to promote chromatin looping and transcriptional activation.