Expression of ATP13A2 protects against various cellular insults. NLF stable clones expressing WT ATP13A2 (clones NLF-P9 No. 1, NLF-P9 No. 3, and NLF-P9 No. 14) and native NLF cells were treated for 24 hr with various concentrations of H2O2 (A), MPP+ (B), rotenone (C), or MG132 (D). Trypan blue exclusion assays were performed to assess viability. Results are plotted as the percentage of dead cells. Error bars represent SEM (n = 6). ★P = 0.01.