Table 1.
GLA 5′UTR plasmid vector constructs | Cell lines | |||||||
---|---|---|---|---|---|---|---|---|
HEK-293 | HeLa | HDMEC | Jurkat | |||||
N | Mean rank (nRLA) | N | Mean rank (nRLA) | N | Mean rank (nRLA) | N | Mean rank (nRLA) | |
WT | 13 | 20.54 | 16 | 38.03 | 15 | 45.23 | 15 | 45.17 |
c.-10T | 13 | 46.62 | 16 | 48.28 | 15 | 39.77 | 15 | 27.07 |
c.-12A | 13 | 30.92 | 16 | 28.69 | 15 | 26.73 | 15 | 27.83 |
c.-30A | 13 | 25.96 | 12 | 10.00 | 15 | 48.60 | 9 | 23.94 |
c.-44T | 13 | 40.96 | 16 | 60.38 | 15 | 29.67 | 15 | 46.57 |
Total (N) | 65 | 76 | 75 | 69 | ||||
Kruskal–Wallis test | ||||||||
Chi-square (df = 4) | 16.652 | 41.993 | 11.501 | 15.831 | ||||
Asymptotic significance | 0.002 | 0.000 | 0.021 | 0.003 |
WT wild-type, N number of experiments validated per each cell line, df degrees of freedom