Table 2.

Summary of meta-analysis results: categorical and continuous outcomes

	Outcome	Included studies, n	Intervention		Control		Risk ratio M-H, random (95% CI)	Heterogeneity, I2
			Events	Total	Events	Total
At 4.7–6 years: categorical outcomes
Mortality	Mortality (all-cause)	4	199	1402	253	1401	0.79 (0.66 to 0.93)	0%
	Cardiac cause of death	4	128	1384	174	1385	0.74 (0.58 to 0.94)	12%
Risk factor management	BP within guidelines	3	624	1016	623	1005	0.95 (0.83 to 1.09)	61%
	Total cholesterol within guidelines	3	417	950	397	879	0.98 (0.89 to 1.07)	0%
Secondary prevention prescribing	Aspirin prescribed	3	687	958	631	939	1.06 (1.00 to 1.12)	39%
	Statins prescribed	2	212	472	213	493	1.09 (0.77 to 1.53)	75%
At 10 years: categorical outcomes
Mortality	Mortality (all-cause)	2	257	672	283	674	0.91 (0.75 to 1.09)	3%
	Cardiac cause of death	2	152	672	160	674	0.95 (0.79 to 1.16)	0%
At 4.7–6 years: continuous outcomes
	Outcome	Included studies, n	Intervention, n		Control, n		Mean differenceb (95% CI)	Heterogeneity, I2
Risk factor management	Mean difference systolic BP (mmHg)	2	469		466		1.94 (−3.02 to 6.91)	70%
	Mean difference total cholesterol (mmol/l)	2	362		358		0.03 (−0.12 to 0.18)	0%

BP = blood pressure.

^aMantel-Haenszel, random effects.

^bInverse variance, random effects.