Table 1.
Human nuclear DNA content and cell volume data
| Cell type | Cell/nuclear size (original values) | DNA content (original values) | Size, content (original units) | Cell volume (μ3) | DNA content (pg) | Sources |
|---|---|---|---|---|---|---|
| Amnion epithelial cell (s) | 3.0 | 40.7 | c, a | 1072.1 | 5.9 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 2.6 | 41.6 | c, a | 958.0 | 6.0 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 2.9 | 41.7 | c, a | 1048.5 | 6.0 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 4.0 | 42.4 | c, a | 1437.0 | 6.1 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 3.4 | 42.7 | c, a | 1227.5 | 6.2 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 2.5 | 43.0 | c, a | 895.3 | 6.2 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 2.5 | 43.0 | c, a | 915.8 | 6.2 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 2.7 | 44.0 | c, a | 968.9 | 6.4 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 2.8 | 44.6 | c, a | 1002.2 | 6.5 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 2.9 | 44.6 | c, a | 1036.5 | 6.5 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 3.2 | 44.7 | c, a | 1147.2 | 6.5 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 4.0 | 45.4 | c, a | 1437.0 | 6.6 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 2.6 | 45.5 | c, a | 936.7 | 6.6 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 2.9 | 45.6 | c, a | 1036.5 | 6.6 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 3.6 | 46.8 | c, a | 1298.5 | 6.8 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 3.0 | 47.2 | c, a | 1072.1 | 6.8 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 2.4 | 47.6 | c, a | 865.5 | 6.9 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 2.8 | 47.7 | c, a | 1002.2 | 6.9 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 2.8 | 47.7 | c, a | 1013.5 | 6.9 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 3.9 | 48.0 | c, a | 1405.1 | 7.0 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 4.7 | 48.7 | c, a | 1682.4 | 7.1 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 2.7 | 48.8 | c, a | 968.9 | 7.1 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 2.9 | 48.8 | c, a | 1036.5 | 7.1 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 3.1 | 48.9 | c, a | 1109.2 | 7.1 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 3.8 | 49.1 | c, a | 1373.6 | 7.1 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 2.6 | 49.3 | c, a | 936.7 | 7.1 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 2.8 | 49.4 | c, a | 1013.5 | 7.2 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 2.7 | 49.9 | c, a | 968.9 | 7.2 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 4.2 | 50.3 | c, a | 1503.2 | 7.3 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 2.9 | 50.5 | c, a | 1036.5 | 7.3 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 3.1 | 50.6 | c, a | 1134.2 | 7.3 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 3.4 | 50.7 | c, a | 1213.8 | 7.3 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 2.5 | 51.0 | c, a | 905.6 | 7.4 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 4.0 | 52.0 | c, a | 1437.0 | 7.5 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 2.7 | 52.2 | c, a | 968.9 | 7.6 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 3.2 | 52.4 | c, a | 1173.3 | 7.6 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 3.5 | 53.0 | c, a | 1255.3 | 7.7 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 1.8 | 53.0 | c, a | 660.8 | 7.7 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 4.4 | 53.2 | c, a | 1572.4 | 7.7 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 3.0 | 53.5 | c, a | 1072.1 | 7.8 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 3.9 | 53.8 | c, a | 1405.1 | 7.8 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 3.9 | 54.4 | c, a | 1389.4 | 7.9 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 3.5 | 54.9 | c, a | 1255.3 | 8.0 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 3.2 | 57.4 | c, a | 1173.3 | 8.3 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 3.9 | 58.2 | c, a | 1405.1 | 8.4 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 3.6 | 62.2 | c, a | 1313.2 | 9.0 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 3.8 | 64.4 | c, a | 1373.6 | 9.3 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 3.9 | 71.4 | c, a | 1389.4 | 10.3 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 3.8 | 80.8 | c, a | 1358.1 | 11.7 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 3.6 | 82.6 | c, a | 1313.2 | 12.0 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 4.3 | 85.7 | c, a | 1537.5 | 12.4 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 3.8 | 87.5 | c, a | 1358.1 | 12.7 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 5.6 | 89.1 | c, a | 1992.2 | 12.9 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 4.0 | 89.6 | c, a | 1420.9 | 13.0 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 5.3 | 90.1 | c, a | 1904.3 | 13.1 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 4.5 | 91.9 | c, a | 1608.4 | 13.3 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 4.0 | 92.7 | c, a | 1420.9 | 13.4 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 4.3 | 93.9 | c, a | 1537.5 | 13.6 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 4.6 | 94.0 | c, a | 1663.6 | 13.6 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 4.2 | 97.1 | c, a | 1520.3 | 14.1 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 5.8 | 97.7 | c, a | 2060.6 | 14.2 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 4.9 | 98.5 | c, a | 1760.2 | 14.3 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 5.5 | 98.7 | c, a | 1970.0 | 14.3 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 4.3 | 100.5 | c, a | 1537.5 | 14.6 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 5.8 | 101.0 | c, a | 2060.6 | 14.6 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 5.1 | 102.0 | c, a | 1820.4 | 14.8 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 6.0 | 102.2 | c, a | 2131.4 | 14.8 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 4.6 | 102.9 | c, a | 1645.1 | 14.9 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 5.7 | 104.5 | c, a | 2014.8 | 15.1 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 5.1 | 106.7 | c, a | 1820.4 | 15.5 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 5.3 | 106.8 | c, a | 1883.0 | 15.5 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 5.0 | 107.9 | c, a | 1780.0 | 15.6 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 4.9 | 109.1 | c, a | 1740.3 | 15.8 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 6.9 | 114.8 | c, a | 2439.8 | 16.6 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 5.5 | 115.7 | c, a | 1970.0 | 16.8 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 6.7 | 118.7 | c, a | 2358.9 | 17.2 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 7.2 | 120.2 | c, a | 2552.4 | 17.4 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 5.9 | 124.0 | c, a | 2107.4 | 18.0 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 5.7 | 126.7 | c, a | 2014.8 | 18.4 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 5.9 | 132.7 | c, a | 2107.4 | 19.2 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 7.0 | 142.5 | c, a | 2467.4 | 20.7 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 7.8 | 149.4 | c, a | 2761.6 | 21.7 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 7.6 | 156.3 | c, a | 2700.3 | 22.7 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 8.7 | 171.5 | c, a | 3056.5 | 24.9 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 7.8 | 185.4 | c, a | 2761.6 | 26.9 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 8.3 | 185.5 | c, a | 2921.7 | 26.9 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 8.9 | 187.9 | c, a | 3126.2 | 27.2 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 8.3 | 192.0 | c, a | 2921.7 | 27.8 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 7.3 | 209.8 | c, a | 2581.4 | 30.4 | Klinger and Schwarzacher 1960 |
| Amnion epithelial cell (s) | 6.8 | 224.3 | c, a | 2412.5 | 32.5 | Klinger and Schwarzacher 1960 |
| Cardiomyocyte (m) | 17401.0 | 20.0 | v, pg | 5646.7 | 20.0 | Vliegen et al. 1990 |
| Cardiomyocyte (m) | 20794.0 | 21.2 | v, pg | 6339.9 | 21.2 | Vliegen et al. 1990 |
| Cardiomyocyte (m) | 43.8 | 3.6 | cc, p | 1463.2 | 12.6 | Wohlschlaeger et al. 2010 |
| Cardiomyocyte (m) | 60.7 | 4.1 | cc, p | 2013.5 | 14.4 | Wohlschlaeger et al. 2010 |
| Cardiomyocyte (m) | 55.5 | 4.5 | cc, p | 1844.6 | 15.8 | Wohlschlaeger et al. 2010 |
| Cardiomyocyte (m) | 135.5 | 4.6 | cc, p | 4403.8 | 16.1 | Wohlschlaeger et al. 2010 |
| Cardiomyocyte (m) | 156.4 | 5.1 | cc, p | 5064.6 | 17.9 | Wohlschlaeger et al. 2010 |
| Cardiomyocyte (m) | 127.0 | 5.8 | cc, p | 4132.1 | 20.2 | Wohlschlaeger et al. 2010 |
| Cardiomyocyte (m) | 65.1 | 5.9 | cc, p | 2154.9 | 20.7 | Wohlschlaeger et al. 2010 |
| Cardiomyocyte (m) | 68.1 | 5.9 | cc, p | 2252.3 | 20.7 | Wohlschlaeger et al. 2010 |
| Cardiomyocyte (m) | 77.3 | 5.9 | cc, p | 2546.1 | 20.7 | Wohlschlaeger et al. 2010 |
| Cardiomyocyte (m) | 71.1 | 6.0 | cc, p | 2346.7 | 21.0 | Wohlschlaeger et al. 2010 |
| Cardiomyocyte (m) | 119.2 | 6.6 | cc, p | 3885.0 | 23.1 | Wohlschlaeger et al. 2010 |
| Cardiomyocyte (m) | 60.3 | 6.8 | cc, p | 2000.2 | 23.8 | Wohlschlaeger et al. 2010 |
| Cardiomyocyte (m) | 84.1 | 7.2 | cc, p | 2765.2 | 25.2 | Wohlschlaeger et al. 2010 |
| Cardiomyocyte (m) | 103.7 | 7.9 | cc, p | 3392.5 | 27.6 | Wohlschlaeger et al. 2010 |
| Cardiomyocyte (m) | 104.0 | 7.9 | cc, p | 3402.4 | 27.7 | Wohlschlaeger et al. 2010 |
| Cardiomyocyte (m) | 112.1 | 8.4 | cc, p | 3658.9 | 29.4 | Wohlschlaeger et al. 2010 |
| Cardiomyocyte (m) | 99.8 | 8.5 | cc, p | 3266.2 | 29.8 | Wohlschlaeger et al. 2010 |
| Cardiomyocyte (m) | 161.5 | 8.6 | cc, p | 5224.0 | 30.1 | Wohlschlaeger et al. 2010 |
| Cardiomyocyte (m) | 152.5 | 8.8 | cc, p | 4939.6 | 30.8 | Wohlschlaeger et al. 2010 |
| Cardiomyocyte (m) | 105.1 | 9.0 | cc, p | 3436.8 | 31.5 | Wohlschlaeger et al. 2010 |
| Cardiomyocyte (m) | 175.4 | 9.5 | cc, p | 5660.7 | 33.3 | Wohlschlaeger et al. 2010 |
| Cardiomyocyte (m) | 97.6 | 11.9 | cc, p | 3198.5 | 41.7 | Wohlschlaeger et al. 2010 |
| Cardiomyocyte (m) | 129.9 | 13.6 | cc, p | 4225.6 | 47.6 | Wohlschlaeger et al. 2010 |
| Cytotrophoblast (m) | 133.0 | 1.9 | cc, p | 1061.5 | 6.7 | Galton 1962 |
| Cytotrophoblast (m) | 109.0 | 2.1 | cc, p | 932.7 | 7.4 | Galton 1962 |
| Cytotrophoblast (m) | 125.0 | 2.4 | cc, p | 1019.6 | 8.3 | Galton 1962 |
| Cytotrophoblast (m) | 128.0 | 2.4 | cc, p | 1035.4 | 8.5 | Galton 1962 |
| Endocrine pancreatic cell (m) | 98.4 | 2.0 | cc, p | 872.7 | 7.0 | Ehrie and Swartz 1974 |
| Endocrine pancreatic cell (m) | 116.5 | 2.0 | cc, p | 973.9 | 7.0 | Ehrie and Swartz 1974 |
| Endocrine pancreatic cell (m) | 119.0 | 2.0 | cc, p | 987.5 | 7.0 | Ehrie and Swartz 1974 |
| Endocrine pancreatic cell (m) | 205.4 | 4.0 | cc, p | 1408.0 | 14.0 | Ehrie and Swartz 1974 |
| Endocrine pancreatic cell (m) | 217.8 | 4.0 | cc, p | 1462.7 | 14.0 | Ehrie and Swartz 1974 |
| Endocrine pancreatic cell (m) | 221.8 | 4.0 | cc, p | 1480.1 | 14.0 | Ehrie and Swartz 1974 |
| Endocrine pancreatic cell (m) | 435.5 | 8.0 | cc, p | 2294.9 | 28.0 | Ehrie and Swartz 1974 |
| Endocrine pancreatic cell (m) | 447.3 | 8.0 | cc, p | 2335.1 | 28.0 | Ehrie and Swartz 1974 |
| Endocrine pancreatic cell (m) | 453.1 | 8.0 | cc, p | 2354.8 | 28.0 | Ehrie and Swartz 1974 |
| Endothelial cell (m) | 36.5 | 4.2 | cc, pg | 1225.4 | 4.2 | Dorman et al. 1990 |
| Endothelial cell (m) | 42.4 | 4.2 | cc, pg | 1418.2 | 4.2 | Dorman et al. 1990 |
| Endothelial cell (m) | 41.1 | 4.6 | cc, pg | 1375.8 | 4.6 | Dorman et al. 1990 |
| Endothelial cell (m) | 63.5 | 5.3 | cc, pg | 2102.6 | 5.3 | Dorman et al. 1990 |
| Exocrine pancreatic cell (m) | 100.1 | 2.0 | cc, p | 882.5 | 7.0 | Ehrie and Swartz 1974 |
| Exocrine pancreatic cell (m) | 107.7 | 2.0 | cc, p | 925.5 | 7.0 | Ehrie and Swartz 1974 |
| Exocrine pancreatic cell (m) | 112.8 | 2.0 | cc, p | 953.7 | 7.0 | Ehrie and Swartz 1974 |
| Hepatic parenchymal cell (m) | 34.7 | 1.8 | cc, a | 1124.6 | 4.8 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 34.4 | 2.0 | cc, a | 1118.2 | 5.4 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 45.1 | 2.1 | cc, a | 1333.5 | 5.6 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 34.8 | 2.3 | cc, a | 1126.7 | 6.1 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 26.1 | 2.3 | cc, a | 934.6 | 6.2 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 38.9 | 2.3 | cc, a | 1211.3 | 6.2 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 37.9 | 2.3 | cc, a | 1191.0 | 6.3 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 36.6 | 2.4 | cc, a | 1164.2 | 6.5 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 33.9 | 2.5 | cc, a | 1107.7 | 6.6 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 33.2 | 2.5 | cc, a | 1092.8 | 6.6 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 32.9 | 2.5 | cc, a | 1086.3 | 6.7 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 41.7 | 2.5 | cc, a | 1267.3 | 6.7 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 27.6 | 2.5 | cc, a | 969.1 | 6.8 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 51.2 | 2.5 | cc, a | 1448.1 | 6.8 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 35.2 | 2.6 | cc, a | 1135.1 | 6.8 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 41.8 | 2.6 | cc, a | 1269.2 | 6.9 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 29.5 | 2.6 | cc, a | 1012.0 | 7.0 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 29.4 | 2.6 | cc, a | 1009.7 | 7.1 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 40.4 | 2.6 | cc, a | 1241.5 | 7.1 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 47.4 | 2.7 | cc, a | 1377.3 | 7.2 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 39.9 | 2.7 | cc, a | 1231.4 | 7.2 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 32.5 | 2.7 | cc, a | 1077.7 | 7.2 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 55.3 | 2.7 | cc, a | 1522.5 | 7.2 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 30.6 | 2.7 | cc, a | 1036.3 | 7.4 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 36.9 | 2.8 | cc, a | 1170.5 | 7.4 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 22.3 | 2.8 | cc, a | 843.7 | 7.5 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 36.4 | 2.8 | cc, a | 1160.1 | 7.5 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 28.1 | 2.8 | cc, a | 980.5 | 7.5 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 33.9 | 2.8 | cc, a | 1107.7 | 7.5 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 54.5 | 2.8 | cc, a | 1508.1 | 7.5 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 38.6 | 2.9 | cc, a | 1205.2 | 7.7 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 49.3 | 2.9 | cc, a | 1413.0 | 7.7 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 36.1 | 2.9 | cc, a | 1153.9 | 7.7 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 44.6 | 2.9 | cc, a | 1323.9 | 7.8 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 33.3 | 2.9 | cc, a | 1094.9 | 7.9 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 31.4 | 3.1 | cc, a | 1053.9 | 8.4 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 36.0 | 3.2 | cc, a | 1151.8 | 8.5 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 71.4 | 3.4 | cc, a | 1797.6 | 9.1 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 98.7 | 3.8 | cc, a | 2218.6 | 10.1 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 78.1 | 4.4 | cc, a | 1905.5 | 11.8 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 44.5 | 4.8 | cc, a | 1321.9 | 12.8 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 65.8 | 4.8 | cc, a | 1704.6 | 12.9 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 71.6 | 4.9 | cc, a | 1800.8 | 13.1 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 65.0 | 5.0 | cc, a | 1691.1 | 13.3 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 69.0 | 5.1 | cc, a | 1758.1 | 13.7 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 64.1 | 5.2 | cc, a | 1675.9 | 13.9 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 72.9 | 5.3 | cc, a | 1822.0 | 14.1 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 70.7 | 5.3 | cc, a | 1786.1 | 14.1 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 91.7 | 5.3 | cc, a | 2115.0 | 14.2 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 87.0 | 5.4 | cc, a | 2043.9 | 14.5 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 78.4 | 5.4 | cc, a | 1910.2 | 14.5 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 147.2 | 5.4 | cc, a | 2876.9 | 14.5 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 70.3 | 5.5 | cc, a | 1779.5 | 14.7 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 81.6 | 5.6 | cc, a | 1960.6 | 15.0 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 72.9 | 5.7 | cc, a | 1822.0 | 15.2 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 73.6 | 6.1 | cc, a | 1833.4 | 16.4 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 65.3 | 6.4 | cc, a | 1696.2 | 17.2 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 177.5 | 7.4 | cc, a | 3249.1 | 19.9 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 106.7 | 9.3 | cc, a | 2333.9 | 24.9 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 129.4 | 9.8 | cc, a | 2645.7 | 26.2 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 141.9 | 9.8 | cc, a | 2809.1 | 26.4 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 136.8 | 9.9 | cc, a | 2743.1 | 26.5 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 142.1 | 11.6 | cc, a | 2811.7 | 31.1 | Swartz 1956 |
| Hepatic parenchymal cell (m) | 144.7 | 13.6 | cc, a | 2845.0 | 36.6 | Swartz 1956 |
| Hepatocyte (s) | 35.7 | 18.3 | cc, a | 1200.9 | 8.7 | Meek and Harbison 1967 |
| Hepatocyte (s) | 46.1 | 20.7 | cc, a | 1537.3 | 9.9 | Meek and Harbison 1967 |
| Hepatocyte (s) | 41.9 | 21.0 | cc, a | 1400.8 | 10.0 | Meek and Harbison 1967 |
| Hepatocyte (s) | 59.3 | 22.4 | cc, a | 1965.6 | 10.7 | Meek and Harbison 1967 |
| Hepatocyte (s) | 39.0 | 22.6 | cc, a | 1306.2 | 10.8 | Meek and Harbison 1967 |
| Hepatocyte (s) | 42.2 | 23.6 | cc, a | 1411.4 | 11.3 | Meek and Harbison 1967 |
| Hepatocyte (s) | 73.4 | 23.8 | cc, a | 2422.6 | 11.4 | Meek and Harbison 1967 |
| Hepatocyte (s) | 64.7 | 24.4 | cc, a | 2142.5 | 11.6 | Meek and Harbison 1967 |
| Hepatocyte (s) | 46.7 | 25.6 | cc, a | 1558.2 | 12.2 | Meek and Harbison 1967 |
| Hepatocyte (s) | 68.0 | 25.8 | cc, a | 2246.3 | 12.3 | Meek and Harbison 1967 |
| Hepatocyte (s) | 64.1 | 26.7 | cc, a | 2121.7 | 12.7 | Meek and Harbison 1967 |
| Hepatocyte (s) | 89.5 | 29.5 | cc, a | 2939.3 | 14.1 | Meek and Harbison 1967 |
| Hepatocyte (s) | 54.1 | 30.6 | cc, a | 1798.8 | 14.6 | Meek and Harbison 1967 |
| Hepatocyte (s) | 73.1 | 32.1 | cc, a | 2412.3 | 15.3 | Meek and Harbison 1967 |
| Hepatocyte (s) | 89.5 | 32.5 | cc, a | 2939.3 | 15.5 | Meek and Harbison 1967 |
| Hepatocyte (s) | 64.1 | 33.3 | cc, a | 2121.7 | 15.9 | Meek and Harbison 1967 |
| Hepatocyte (s) | 73.1 | 34.4 | cc, a | 2412.3 | 16.4 | Meek and Harbison 1967 |
| Hepatocyte (s) | 96.3 | 35.8 | cc, a | 3155.6 | 17.1 | Meek and Harbison 1967 |
| Hepatocyte (s) | 53.8 | 35.9 | cc, a | 1788.3 | 17.1 | Meek and Harbison 1967 |
| Hepatocyte (s) | 68.0 | 38.3 | cc, a | 2246.3 | 18.2 | Meek and Harbison 1967 |
| Hepatocyte (s) | 84.1 | 39.1 | cc, a | 2763.9 | 18.6 | Meek and Harbison 1967 |
| Hepatocyte (s) | 78.9 | 39.7 | cc, a | 2598.6 | 18.9 | Meek and Harbison 1967 |
| Hepatocyte (s) | 63.8 | 39.9 | cc, a | 2111.3 | 19.0 | Meek and Harbison 1967 |
| Hepatocyte (s) | 68.3 | 40.3 | cc, a | 2256.7 | 19.2 | Meek and Harbison 1967 |
| Hepatocyte (s) | 72.8 | 40.9 | cc, a | 2401.9 | 19.5 | Meek and Harbison 1967 |
| Hepatocyte (s) | 113.4 | 41.9 | cc, a | 3699.8 | 19.9 | Meek and Harbison 1967 |
| Hepatocyte (s) | 126.2 | 43.3 | cc, a | 4109.2 | 20.6 | Meek and Harbison 1967 |
| Hepatocyte (s) | 90.2 | 43.7 | cc, a | 2959.9 | 20.8 | Meek and Harbison 1967 |
| Hepatocyte (s) | 106.9 | 44.1 | cc, a | 3494.7 | 21.0 | Meek and Harbison 1967 |
| Hepatocyte (s) | 101.1 | 45.7 | cc, a | 3309.8 | 21.8 | Meek and Harbison 1967 |
| Hepatocyte (s) | 96.0 | 47.0 | cc, a | 3145.3 | 22.4 | Meek and Harbison 1967 |
| Hepatocyte (s) | 90.2 | 47.6 | cc, a | 2959.9 | 22.7 | Meek and Harbison 1967 |
| Hepatocyte (s) | 140.1 | 48.0 | cc, a | 4548.1 | 22.9 | Meek and Harbison 1967 |
| Hepatocyte (s) | 95.3 | 48.7 | cc, a | 3124.7 | 23.2 | Meek and Harbison 1967 |
| Hepatocyte (s) | 107.2 | 49.1 | cc, a | 3504.9 | 23.4 | Meek and Harbison 1967 |
| Hepatocyte (s) | 120.8 | 49.8 | cc, a | 3935.3 | 23.7 | Meek and Harbison 1967 |
| Hepatocyte (s) | 90.2 | 50.3 | cc, a | 2959.9 | 23.9 | Meek and Harbison 1967 |
| Hepatocyte (s) | 140.1 | 50.9 | cc, a | 4548.1 | 24.3 | Meek and Harbison 1967 |
| Hepatocyte (s) | 101.4 | 52.7 | cc, a | 3320.1 | 25.1 | Meek and Harbison 1967 |
| Hepatocyte (s) | 113.7 | 53.4 | cc, a | 3710.1 | 25.4 | Meek and Harbison 1967 |
| Hepatocyte (s) | 156.2 | 56.6 | cc, a | 5057.1 | 27.0 | Meek and Harbison 1967 |
| Hepatocyte (s) | 113.0 | 58.7 | cc, a | 3689.5 | 27.9 | Meek and Harbison 1967 |
| Hepatocyte (s) | 120.8 | 63.0 | cc, a | 3935.3 | 30.0 | Meek and Harbison 1967 |
| Hepatocyte (s) | 140.7 | 79.6 | cc, a | 4568.4 | 37.9 | Meek and Harbison 1967 |
| Hepatocyte (s) | 170.4 | 91.6 | cc, a | 5503.9 | 43.6 | Meek and Harbison 1967 |
| Hepatocyte (s) | 177.5 | 97.9 | cc, a | 5726.9 | 46.6 | Meek and Harbison 1967 |
| Lymphocyte (m) | 17.9 | 4.0 | cc, pg | 611.8 | 4.0 | Dorman et al. 1990 |
| Lymphocyte (m) | 19.8 | 4.0 | cc, pg | 675.0 | 4.0 | Dorman et al. 1990 |
| Lymphocyte (m) | 18.5 | 4.2 | cc, pg | 631.8 | 4.2 | Dorman et al. 1990 |
| Lymphocyte (m) | 37.6 | 5.8 | cc, pg | 1261.4 | 5.8 | Dorman et al. 1990 |
| Lymphocyte (s) | 18.1 | 17.2 | cc, a | 618.7 | 6.3 | Bedi and Goldstein 1976 |
| Lymphocyte (s) | 19.9 | 17.4 | cc, a | 679.4 | 6.3 | Bedi and Goldstein 1976 |
| Lymphocyte (s) | 18.6 | 17.7 | cc, a | 633.9 | 6.4 | Bedi and Goldstein 1976 |
| Lymphocyte (s) | 23.5 | 18.5 | cc, a | 796.5 | 6.7 | Bedi and Goldstein 1976 |
| Lymphocyte (s) | 21.2 | 18.6 | cc, a | 721.0 | 6.7 | Bedi and Goldstein 1976 |
| Lymphocyte (s) | 22.8 | 18.8 | cc, a | 773.8 | 6.8 | Bedi and Goldstein 1976 |
| Lymphocyte (s) | 21.4 | 18.9 | cc, a | 728.5 | 6.9 | Bedi and Goldstein 1976 |
| Lymphocyte (s) | 22.9 | 18.9 | cc, a | 777.6 | 6.9 | Bedi and Goldstein 1976 |
| Lymphocyte (s) | 24.9 | 19.0 | cc, a | 845.4 | 6.9 | Bedi and Goldstein 1976 |
| Lymphocyte (s) | 22.4 | 19.0 | cc, a | 762.5 | 6.9 | Bedi and Goldstein 1976 |
| Lymphocyte (s) | 24.3 | 19.0 | cc, a | 822.9 | 6.9 | Bedi and Goldstein 1976 |
| Lymphocyte (s) | 23.0 | 19.1 | cc, a | 781.4 | 6.9 | Bedi and Goldstein 1976 |
| Lymphocyte (s) | 22.8 | 19.3 | cc, a | 773.8 | 7.0 | Bedi and Goldstein 1976 |
| Lymphocyte (s) | 23.8 | 19.7 | cc, a | 807.8 | 7.1 | Bedi and Goldstein 1976 |
| Lymphocyte (s) | 28.0 | 19.9 | cc, a | 946.9 | 7.2 | Bedi and Goldstein 1976 |
| Lymphocyte (s) | 7.4 | 2.7 | n, a | 1437.3 | 4.1 | Petrakis 1953 |
| Lymphocyte (s) | 5.5 | 3.0 | n, a | 793.2 | 4.5 | Petrakis 1953 |
| Lymphocyte (s) | 7.0 | 3.0 | n, a | 1293.6 | 4.6 | Petrakis 1953 |
| Lymphocyte (s) | 5.2 | 3.0 | n, a | 712.0 | 4.6 | Petrakis 1953 |
| Lymphocyte (s) | 7.7 | 3.0 | n, a | 1562.6 | 4.6 | Petrakis 1953 |
| Lymphocyte (s) | 7.5 | 3.1 | n, a | 1462.0 | 4.7 | Petrakis 1953 |
| Lymphocyte (s) | 7.0 | 3.1 | n, a | 1278.2 | 4.8 | Petrakis 1953 |
| Lymphocyte (s) | 7.1 | 3.1 | n, a | 1340.8 | 4.8 | Petrakis 1953 |
| Lymphocyte (s) | 5.6 | 3.2 | n, a | 824.1 | 4.8 | Petrakis 1953 |
| Lymphocyte (s) | 7.0 | 3.3 | n, a | 1293.6 | 5.0 | Petrakis 1953 |
| Lymphocyte (s) | 8.0 | 3.3 | n, a | 1666.4 | 5.0 | Petrakis 1953 |
| Lymphocyte (s) | 7.5 | 3.3 | n, a | 1462.0 | 5.0 | Petrakis 1953 |
| Lymphocyte (s) | 8.2 | 3.3 | n, a | 1746.7 | 5.0 | Petrakis 1953 |
| Lymphocyte (s) | 7.8 | 3.4 | n, a | 1597.1 | 5.2 | Petrakis 1953 |
| Lymphocyte (s) | 6.5 | 3.4 | n, a | 1118.1 | 5.2 | Petrakis 1953 |
| Lymphocyte (s) | 6.9 | 3.5 | n, a | 1239.8 | 5.3 | Petrakis 1953 |
| Lymphocyte (s) | 7.7 | 3.5 | n, a | 1562.6 | 5.3 | Petrakis 1953 |
| Lymphocyte (s) | 8.0 | 3.5 | n, a | 1666.4 | 5.3 | Petrakis 1953 |
| Lymphocyte (s) | 7.5 | 3.5 | n, a | 1495.0 | 5.3 | Petrakis 1953 |
| Lymphocyte (s) | 5.0 | 3.5 | n, a | 680.8 | 5.4 | Petrakis 1953 |
| Lymphocyte (s) | 6.0 | 3.5 | n, a | 953.5 | 5.4 | Petrakis 1953 |
| Lymphocyte (s) | 7.4 | 3.5 | n, a | 1453.6 | 5.4 | Petrakis 1953 |
| Lymphocyte (s) | 6.5 | 3.6 | n, a | 1118.1 | 5.4 | Petrakis 1953 |
| Lymphocyte (s) | 5.0 | 3.6 | n, a | 671.6 | 5.5 | Petrakis 1953 |
| Lymphocyte (s) | 8.2 | 3.6 | n, a | 1737.6 | 5.5 | Petrakis 1953 |
| Lymphocyte (s) | 6.0 | 3.6 | n, a | 950.4 | 5.5 | Petrakis 1953 |
| Lymphocyte (s) | 7.0 | 3.6 | n, a | 1293.6 | 5.5 | Petrakis 1953 |
| Lymphocyte (s) | 7.5 | 3.7 | n, a | 1462.0 | 5.6 | Petrakis 1953 |
| Lymphocyte (s) | 7.8 | 3.7 | n, a | 1579.6 | 5.6 | Petrakis 1953 |
| Lymphocyte (s) | 7.0 | 3.7 | n, a | 1286.0 | 5.7 | Petrakis 1953 |
| Lymphocyte (s) | 5.0 | 3.7 | n, a | 671.6 | 5.7 | Petrakis 1953 |
| Lymphocyte (s) | 6.2 | 3.8 | n, a | 1028.4 | 5.8 | Petrakis 1953 |
| Lymphocyte (s) | 6.0 | 3.8 | n, a | 956.9 | 5.8 | Petrakis 1953 |
| Lymphocyte (s) | 6.0 | 3.8 | n, a | 953.5 | 5.8 | Petrakis 1953 |
| Lymphocyte (s) | 6.6 | 3.8 | n, a | 1142.7 | 5.8 | Petrakis 1953 |
| Lymphocyte (s) | 7.1 | 3.8 | n, a | 1317.1 | 5.8 | Petrakis 1953 |
| Lymphocyte (s) | 6.5 | 3.8 | n, a | 1113.7 | 5.8 | Petrakis 1953 |
| Lymphocyte (s) | 6.0 | 3.9 | n, a | 953.5 | 5.9 | Petrakis 1953 |
| Lymphocyte (s) | 10.1 | 3.9 | n, a | 2627.9 | 5.9 | Petrakis 1953 |
| Lymphocyte (s) | 6.8 | 3.9 | n, a | 1217.0 | 5.9 | Petrakis 1953 |
| Lymphocyte (s) | 6.1 | 3.9 | n, a | 980.3 | 5.9 | Petrakis 1953 |
| Lymphocyte (s) | 6.3 | 3.9 | n, a | 1035.5 | 6.0 | Petrakis 1953 |
| Lymphocyte (s) | 7.2 | 3.9 | n, a | 1364.7 | 6.0 | Petrakis 1953 |
| Lymphocyte (s) | 7.5 | 3.9 | n, a | 1495.0 | 6.0 | Petrakis 1953 |
| Lymphocyte (s) | 7.0 | 3.9 | n, a | 1299.0 | 6.0 | Petrakis 1953 |
| Lymphocyte (s) | 7.2 | 4.0 | n, a | 1370.2 | 6.1 | Petrakis 1953 |
| Lymphocyte (s) | 8.0 | 4.0 | n, a | 1657.9 | 6.1 | Petrakis 1953 |
| Lymphocyte (s) | 8.1 | 4.0 | n, a | 1711.1 | 6.1 | Petrakis 1953 |
| Lymphocyte (s) | 10.0 | 4.0 | n, a | 2594.9 | 6.1 | Petrakis 1953 |
| Lymphocyte (s) | 6.5 | 4.0 | n, a | 1113.7 | 6.1 | Petrakis 1953 |
| Lymphocyte (s) | 6.8 | 4.0 | n, a | 1209.7 | 6.1 | Petrakis 1953 |
| Lymphocyte (s) | 5.6 | 4.0 | n, a | 836.6 | 6.2 | Petrakis 1953 |
| Lymphocyte (s) | 9.0 | 4.1 | n, a | 2115.1 | 6.2 | Petrakis 1953 |
| Lymphocyte (s) | 7.0 | 4.1 | n, a | 1278.2 | 6.2 | Petrakis 1953 |
| Lymphocyte (s) | 6.8 | 4.1 | n, a | 1217.0 | 6.3 | Petrakis 1953 |
| Lymphocyte (s) | 6.0 | 4.2 | n, a | 950.4 | 6.4 | Petrakis 1953 |
| Lymphocyte (s) | 6.5 | 4.2 | n, a | 1113.7 | 6.4 | Petrakis 1953 |
| Lymphocyte (s) | 7.0 | 4.2 | n, a | 1286.0 | 6.4 | Petrakis 1953 |
| Lymphocyte (s) | 7.6 | 4.2 | n, a | 1512.1 | 6.4 | Petrakis 1953 |
| Lymphocyte (s) | 6.6 | 4.2 | n, a | 1142.7 | 6.4 | Petrakis 1953 |
| Lymphocyte (s) | 7.0 | 4.3 | n, a | 1299.0 | 6.5 | Petrakis 1953 |
| Lymphocyte (s) | 7.6 | 4.3 | n, a | 1503.6 | 6.5 | Petrakis 1953 |
| Lymphocyte (s) | 6.0 | 4.3 | n, a | 950.4 | 6.5 | Petrakis 1953 |
| Lymphocyte (s) | 6.9 | 4.3 | n, a | 1252.5 | 6.5 | Petrakis 1953 |
| Lymphocyte (s) | 8.3 | 4.3 | n, a | 1818.2 | 6.6 | Petrakis 1953 |
| Lymphocyte (s) | 6.0 | 4.3 | n, a | 966.9 | 6.6 | Petrakis 1953 |
| Lymphocyte (s) | 6.6 | 4.3 | n, a | 1150.1 | 6.6 | Petrakis 1953 |
| Lymphocyte (s) | 7.0 | 4.3 | n, a | 1286.0 | 6.6 | Petrakis 1953 |
| Lymphocyte (s) | 7.1 | 4.3 | n, a | 1325.1 | 6.6 | Petrakis 1953 |
| Lymphocyte (s) | 7.2 | 4.3 | n, a | 1356.6 | 6.6 | Petrakis 1953 |
| Lymphocyte (s) | 7.5 | 4.4 | n, a | 1485.0 | 6.6 | Petrakis 1953 |
| Lymphocyte (s) | 6.5 | 4.4 | n, a | 1106.4 | 6.7 | Petrakis 1953 |
| Lymphocyte (s) | 7.6 | 4.4 | n, a | 1503.6 | 6.7 | Petrakis 1953 |
| Lymphocyte (s) | 7.4 | 4.4 | n, a | 1435.4 | 6.7 | Petrakis 1953 |
| Lymphocyte (s) | 6.3 | 4.4 | n, a | 1056.6 | 6.7 | Petrakis 1953 |
| Lymphocyte (s) | 6.6 | 4.4 | n, a | 1135.6 | 6.7 | Petrakis 1953 |
| Lymphocyte (s) | 6.0 | 4.4 | n, a | 966.9 | 6.7 | Petrakis 1953 |
| Lymphocyte (s) | 7.0 | 4.4 | n, a | 1299.0 | 6.8 | Petrakis 1953 |
| Lymphocyte (s) | 8.0 | 4.5 | n, a | 1666.4 | 6.8 | Petrakis 1953 |
| Lymphocyte (s) | 9.0 | 4.5 | n, a | 2095.0 | 6.8 | Petrakis 1953 |
| Lymphocyte (s) | 5.5 | 4.5 | n, a | 811.7 | 6.8 | Petrakis 1953 |
| Lymphocyte (s) | 6.2 | 4.5 | n, a | 1014.6 | 6.8 | Petrakis 1953 |
| Lymphocyte (s) | 6.8 | 4.5 | n, a | 1221.9 | 6.8 | Petrakis 1953 |
| Lymphocyte (s) | 7.6 | 4.5 | n, a | 1503.6 | 6.8 | Petrakis 1953 |
| Lymphocyte (s) | 5.8 | 4.5 | n, a | 897.3 | 6.9 | Petrakis 1953 |
| Lymphocyte (s) | 8.0 | 4.6 | n, a | 1666.4 | 6.9 | Petrakis 1953 |
| Lymphocyte (s) | 7.0 | 4.6 | n, a | 1299.0 | 6.9 | Petrakis 1953 |
| Lymphocyte (s) | 7.4 | 4.6 | n, a | 1453.6 | 7.0 | Petrakis 1953 |
| Lymphocyte (s) | 7.8 | 4.6 | n, a | 1588.3 | 7.0 | Petrakis 1953 |
| Lymphocyte (s) | 9.0 | 4.6 | n, a | 2105.0 | 7.0 | Petrakis 1953 |
| Lymphocyte (s) | 8.9 | 4.6 | n, a | 2075.5 | 7.0 | Petrakis 1953 |
| Lymphocyte (s) | 6.1 | 4.6 | n, a | 1000.9 | 7.0 | Petrakis 1953 |
| Lymphocyte (s) | 7.0 | 4.6 | n, a | 1286.0 | 7.0 | Petrakis 1953 |
| Lymphocyte (s) | 6.3 | 4.6 | n, a | 1035.5 | 7.1 | Petrakis 1953 |
| Lymphocyte (s) | 6.6 | 4.6 | n, a | 1150.1 | 7.1 | Petrakis 1953 |
| Lymphocyte (s) | 7.6 | 4.6 | n, a | 1503.6 | 7.1 | Petrakis 1953 |
| Lymphocyte (s) | 6.9 | 4.7 | n, a | 1239.8 | 7.1 | Petrakis 1953 |
| Lymphocyte (s) | 7.8 | 4.7 | n, a | 1605.5 | 7.1 | Petrakis 1953 |
| Lymphocyte (s) | 9.0 | 4.7 | n, a | 2085.5 | 7.1 | Petrakis 1953 |
| Lymphocyte (s) | 7.8 | 4.7 | n, a | 1595.5 | 7.1 | Petrakis 1953 |
| Lymphocyte (s) | 6.2 | 4.7 | n, a | 1007.9 | 7.2 | Petrakis 1953 |
| Lymphocyte (s) | 7.5 | 4.7 | n, a | 1478.5 | 7.2 | Petrakis 1953 |
| Lymphocyte (s) | 8.0 | 4.7 | n, a | 1666.4 | 7.2 | Petrakis 1953 |
| Lymphocyte (s) | 6.5 | 4.7 | n, a | 1132.6 | 7.2 | Petrakis 1953 |
| Lymphocyte (s) | 6.8 | 4.7 | n, a | 1209.7 | 7.2 | Petrakis 1953 |
| Lymphocyte (s) | 7.0 | 4.7 | n, a | 1286.0 | 7.2 | Petrakis 1953 |
| Lymphocyte (s) | 7.4 | 4.7 | n, a | 1437.3 | 7.2 | Petrakis 1953 |
| Lymphocyte (s) | 7.0 | 4.7 | n, a | 1307.0 | 7.2 | Petrakis 1953 |
| Lymphocyte (s) | 7.4 | 4.8 | n, a | 1429.3 | 7.3 | Petrakis 1953 |
| Lymphocyte (s) | 5.8 | 4.8 | n, a | 894.0 | 7.3 | Petrakis 1953 |
| Lymphocyte (s) | 8.0 | 4.8 | n, a | 1675.4 | 7.3 | Petrakis 1953 |
| Lymphocyte (s) | 7.6 | 4.8 | n, a | 1520.3 | 7.3 | Petrakis 1953 |
| Lymphocyte (s) | 7.0 | 4.8 | n, a | 1275.9 | 7.4 | Petrakis 1953 |
| Lymphocyte (s) | 7.0 | 4.9 | n, a | 1291.5 | 7.4 | Petrakis 1953 |
| Lymphocyte (s) | 7.2 | 4.9 | n, a | 1346.3 | 7.4 | Petrakis 1953 |
| Lymphocyte (s) | 7.4 | 4.9 | n, a | 1437.3 | 7.4 | Petrakis 1953 |
| Lymphocyte (s) | 7.5 | 4.9 | n, a | 1470.4 | 7.4 | Petrakis 1953 |
| Lymphocyte (s) | 6.7 | 4.9 | n, a | 1194.4 | 7.5 | Petrakis 1953 |
| Lymphocyte (s) | 9.0 | 4.9 | n, a | 2095.0 | 7.5 | Petrakis 1953 |
| Lymphocyte (s) | 6.0 | 4.9 | n, a | 953.5 | 7.5 | Petrakis 1953 |
| Lymphocyte (s) | 8.0 | 4.9 | n, a | 1666.4 | 7.5 | Petrakis 1953 |
| Lymphocyte (s) | 7.1 | 5.0 | n, a | 1314.9 | 7.6 | Petrakis 1953 |
| Lymphocyte (s) | 8.1 | 5.0 | n, a | 1719.8 | 7.6 | Petrakis 1953 |
| Lymphocyte (s) | 8.0 | 5.0 | n, a | 1666.4 | 7.7 | Petrakis 1953 |
| Lymphocyte (s) | 7.9 | 5.1 | n, a | 1614.3 | 7.7 | Petrakis 1953 |
| Lymphocyte (s) | 6.0 | 5.1 | n, a | 966.9 | 7.7 | Petrakis 1953 |
| Lymphocyte (s) | 7.0 | 5.1 | n, a | 1283.6 | 7.7 | Petrakis 1953 |
| Lymphocyte (s) | 7.0 | 5.1 | n, a | 1293.6 | 7.8 | Petrakis 1953 |
| Lymphocyte (s) | 8.4 | 5.1 | n, a | 1846.4 | 7.8 | Petrakis 1953 |
| Lymphocyte (s) | 7.7 | 5.1 | n, a | 1571.3 | 7.8 | Petrakis 1953 |
| Lymphocyte (s) | 6.6 | 5.1 | n, a | 1150.1 | 7.8 | Petrakis 1953 |
| Lymphocyte (s) | 8.0 | 5.1 | n, a | 1657.9 | 7.8 | Petrakis 1953 |
| Lymphocyte (s) | 8.1 | 5.1 | n, a | 1711.1 | 7.8 | Petrakis 1953 |
| Lymphocyte (s) | 6.8 | 5.2 | n, a | 1224.7 | 7.9 | Petrakis 1953 |
| Lymphocyte (s) | 7.5 | 5.2 | n, a | 1495.0 | 7.9 | Petrakis 1953 |
| Lymphocyte (s) | 8.0 | 5.2 | n, a | 1684.4 | 7.9 | Petrakis 1953 |
| Lymphocyte (s) | 6.0 | 5.2 | n, a | 970.6 | 7.9 | Petrakis 1953 |
| Lymphocyte (s) | 8.0 | 5.3 | n, a | 1691.8 | 8.0 | Petrakis 1953 |
| Lymphocyte (s) | 6.0 | 5.3 | n, a | 940.2 | 8.1 | Petrakis 1953 |
| Lymphocyte (s) | 8.0 | 5.3 | n, a | 1684.4 | 8.1 | Petrakis 1953 |
| Lymphocyte (s) | 8.1 | 5.3 | n, a | 1719.8 | 8.1 | Petrakis 1953 |
| Lymphocyte (s) | 5.6 | 5.4 | n, a | 843.0 | 8.1 | Petrakis 1953 |
| Lymphocyte (s) | 7.0 | 5.4 | n, a | 1307.0 | 8.2 | Petrakis 1953 |
| Lymphocyte (s) | 9.8 | 5.4 | n, a | 2486.4 | 8.2 | Petrakis 1953 |
| Lymphocyte (s) | 9.0 | 5.4 | n, a | 2085.5 | 8.2 | Petrakis 1953 |
| Lymphocyte (s) | 8.0 | 5.4 | n, a | 1674.1 | 8.2 | Petrakis 1953 |
| Lymphocyte (s) | 8.0 | 5.5 | n, a | 1666.4 | 8.3 | Petrakis 1953 |
| Lymphocyte (s) | 7.1 | 5.5 | n, a | 1314.9 | 8.4 | Petrakis 1953 |
| Lymphocyte (s) | 8.0 | 5.5 | n, a | 1691.8 | 8.4 | Petrakis 1953 |
| Lymphocyte (s) | 7.3 | 5.5 | n, a | 1388.8 | 8.4 | Petrakis 1953 |
| Lymphocyte (s) | 8.6 | 5.6 | n, a | 1912.5 | 8.5 | Petrakis 1953 |
| Lymphocyte (s) | 9.0 | 5.6 | n, a | 2095.0 | 8.5 | Petrakis 1953 |
| Lymphocyte (s) | 7.5 | 5.6 | n, a | 1487.0 | 8.5 | Petrakis 1953 |
| Lymphocyte (s) | 7.2 | 5.6 | n, a | 1356.6 | 8.6 | Petrakis 1953 |
| Lymphocyte (s) | 6.1 | 5.7 | n, a | 977.2 | 8.7 | Petrakis 1953 |
| Lymphocyte (s) | 6.8 | 5.7 | n, a | 1229.6 | 8.7 | Petrakis 1953 |
| Lymphocyte (s) | 7.6 | 5.7 | n, a | 1512.1 | 8.7 | Petrakis 1953 |
| Lymphocyte (s) | 8.4 | 5.7 | n, a | 1856.2 | 8.7 | Petrakis 1953 |
| Lymphocyte (s) | 5.6 | 5.8 | n, a | 824.1 | 8.8 | Petrakis 1953 |
| Lymphocyte (s) | 7.1 | 5.8 | n, a | 1309.1 | 8.8 | Petrakis 1953 |
| Lymphocyte (s) | 9.2 | 5.9 | n, a | 2215.0 | 9.0 | Petrakis 1953 |
| Lymphocyte (s) | 6.3 | 6.0 | n, a | 1049.4 | 9.1 | Petrakis 1953 |
| Lymphocyte (s) | 7.8 | 6.0 | n, a | 1597.1 | 9.1 | Petrakis 1953 |
| Lymphocyte (s) | 8.0 | 6.0 | n, a | 1675.4 | 9.1 | Petrakis 1953 |
| Lymphocyte (s) | 8.0 | 6.1 | n, a | 1684.4 | 9.3 | Petrakis 1953 |
| Lymphocyte (s) | 9.0 | 6.1 | n, a | 2095.0 | 9.4 | Petrakis 1953 |
| Lymphocyte (s) | 7.0 | 6.2 | n, a | 1307.0 | 9.5 | Petrakis 1953 |
| Lymphocyte (s) | 6.9 | 6.3 | n, a | 1267.8 | 9.5 | Petrakis 1953 |
| Lymphocyte (s) | 9.2 | 6.3 | n, a | 2205.2 | 9.6 | Petrakis 1953 |
| Lymphocyte (s) | 8.0 | 6.4 | n, a | 1684.4 | 9.7 | Petrakis 1953 |
| Lymphocyte (s) | 9.2 | 6.4 | n, a | 2205.2 | 9.8 | Petrakis 1953 |
| Lymphocyte (s) | 9.2 | 6.5 | n, a | 2215.0 | 9.9 | Petrakis 1953 |
| Lymphocyte (s) | 9.1 | 6.6 | n, a | 2134.8 | 10.0 | Petrakis 1953 |
| Lymphocyte (s) | 8.0 | 6.6 | n, a | 1666.4 | 10.1 | Petrakis 1953 |
| Lymphocyte (s) | 8.0 | 6.7 | n, a | 1666.4 | 10.2 | Petrakis 1953 |
| Lymphocyte (s) | 6.6 | 6.8 | n, a | 1162.1 | 10.4 | Petrakis 1953 |
| Lymphocyte (s) | 9.0 | 6.9 | n, a | 2124.7 | 10.5 | Petrakis 1953 |
| Lymphocyte (s) | 9.1 | 6.9 | n, a | 2164.8 | 10.5 | Petrakis 1953 |
| Lymphocyte (s) | 9.1 | 7.0 | n, a | 2144.5 | 10.7 | Petrakis 1953 |
| Lymphocyte (s) | 11.1 | 7.4 | n, a | 3158.4 | 11.3 | Petrakis 1953 |
| Lymphocyte (s) | 12.1 | 8.5 | n, a | 3762.4 | 13.0 | Petrakis 1953 |
| Lymphocyte polymorph (m) | 25.1 | 17.9 | cc, a | 849.2 | 6.5 | Bedi and Goldstein 1976 |
| Lymphocyte polymorph (m) | 22.8 | 18.0 | cc, a | 773.8 | 6.5 | Bedi and Goldstein 1976 |
| Lymphocyte polymorph (m) | 21.4 | 18.0 | cc, a | 728.5 | 6.5 | Bedi and Goldstein 1976 |
| Lymphocyte polymorph (m) | 20.0 | 18.1 | cc, a | 683.1 | 6.6 | Bedi and Goldstein 1976 |
| Lymphocyte polymorph (m) | 24.4 | 18.2 | cc, a | 826.6 | 6.6 | Bedi and Goldstein 1976 |
| Lymphocyte polymorph (m) | 21.3 | 18.2 | cc, a | 724.8 | 6.6 | Bedi and Goldstein 1976 |
| Lymphocyte polymorph (m) | 27.1 | 18.2 | cc, a | 916.9 | 6.6 | Bedi and Goldstein 1976 |
| Lymphocyte polymorph (m) | 22.9 | 18.5 | cc, a | 777.6 | 6.7 | Bedi and Goldstein 1976 |
| Lymphocyte polymorph (m) | 25.7 | 18.9 | cc, a | 871.8 | 6.9 | Bedi and Goldstein 1976 |
| Lymphocyte polymorph (m) | 28.0 | 19.0 | cc, a | 946.9 | 6.9 | Bedi and Goldstein 1976 |
| Lymphocyte polymorph (m) | 26.2 | 19.0 | cc, a | 886.8 | 6.9 | Bedi and Goldstein 1976 |
| Megakaryocyte (m) | 15.5 | 3.9 | d, p | 1949.8 | 13.7 | Ishibashi et al. 1986 |
| Megakaryocyte (m) | 15.3 | 4.4 | d, p | 1875.3 | 15.4 | Ishibashi et al. 1986 |
| Megakaryocyte (m) | 16.1 | 4.4 | d, p | 2352.1 | 15.4 | Ishibashi et al. 1986 |
| Megakaryocyte (m) | 16.5 | 4.4 | d, p | 2185.1 | 15.4 | Ishibashi et al. 1986 |
| Megakaryocyte (m) | 16.3 | 4.6 | d, p | 2267.6 | 16.1 | Ishibashi et al. 1986 |
| Megakaryocyte (m) | 16.8 | 5.3 | d, p | 2482.7 | 18.6 | Ishibashi et al. 1986 |
| Megakaryocyte (m) | 21.3 | 7.0 | d, p | 5059.8 | 24.5 | Ishibashi et al. 1986 |
| Megakaryocyte (m) | 20.8 | 7.3 | d, p | 4711.8 | 25.6 | Ishibashi et al. 1986 |
| Megakaryocyte (m) | 22.4 | 8.6 | d, p | 5884.9 | 30.1 | Ishibashi et al. 1986 |
| Megakaryocyte (m) | 27.5 | 10.4 | d, p | 10889.2 | 36.4 | Ishibashi et al. 1986 |
| Megakaryocyte (m) | 27.6 | 10.6 | d, p | 11008.4 | 37.1 | Ishibashi et al. 1986 |
| Megakaryocyte (m) | 30.2 | 10.9 | d, p | 14421.8 | 38.2 | Ishibashi et al. 1986 |
| Megakaryocyte (m) | 30.6 | 12.6 | d, p | 15002.5 | 44.1 | Ishibashi et al. 1986 |
| Megakaryocyte (m) | 32.3 | 12.8 | d, p | 17644.4 | 44.8 | Ishibashi et al. 1986 |
| Megakaryocyte (m) | 33.3 | 14.1 | d, p | 19334.4 | 49.4 | Ishibashi et al. 1986 |
| Megakaryocyte (m) | 33.8 | 14.5 | d, p | 20218.5 | 50.8 | Ishibashi et al. 1986 |
| Megakaryocyte (m) | 33.8 | 16.1 | d, p | 20218.5 | 56.4 | Ishibashi et al. 1986 |
| Megakaryocyte (m) | 34.2 | 16.8 | d, p | 20944.8 | 58.8 | Ishibashi et al. 1986 |
| Megakaryocyte (m) | 34.1 | 16.9 | d, p | 20761.6 | 59.2 | Ishibashi et al. 1986 |
| Megakaryocyte (m) | 34.4 | 17.2 | d, p | 21314.4 | 60.2 | Ishibashi et al. 1986 |
| Megakaryocyte (m) | 34.4 | 17.2 | d, p | 21314.4 | 60.2 | Ishibashi et al. 1986 |
| Megakaryocyte (m) | 35.0 | 17.7 | d, p | 22449.3 | 62.0 | Ishibashi et al. 1986 |
| Megakaryocyte (m) | 36.0 | 17.7 | d, p | 24429.0 | 62.0 | Ishibashi et al. 1986 |
| Megakaryocyte (m) | 35.4 | 18.6 | d, p | 23227.8 | 65.1 | Ishibashi et al. 1986 |
| Megakaryocyte (m) | 35.4 | 19.3 | d, p | 23227.8 | 67.6 | Ishibashi et al. 1986 |
| Megakaryocyte (m) | 36.4 | 19.6 | d, p | 25252.4 | 68.6 | Ishibashi et al. 1986 |
| Monocyte (s) | 21.4 | 19.3 | cc, a | 728.5 | 7.0 | Bedi and Goldstein 1976 |
| Monocyte (s) | 32.1 | 19.9 | cc, a | 1081.8 | 7.2 | Bedi and Goldstein 1976 |
| Monocyte (s) | 26.3 | 20.0 | cc, a | 890.6 | 7.3 | Bedi and Goldstein 1976 |
| Monocyte (s) | 30.8 | 20.1 | cc, a | 1036.9 | 7.3 | Bedi and Goldstein 1976 |
| Monocyte (s) | 30.6 | 20.2 | cc, a | 1033.1 | 7.3 | Bedi and Goldstein 1976 |
| Monocyte (s) | 30.9 | 20.3 | cc, a | 1040.7 | 7.4 | Bedi and Goldstein 1976 |
| Monocyte (s) | 46.2 | 21.5 | cc, a | 1543.3 | 7.8 | Bedi and Goldstein 1976 |
| Primary spermatocyte (m) | 37.6 | 2.6 | cc, a | 1184.8 | 7.6 | Leuchtenberger et al. 1956 |
| Primary spermatocyte (m) | 28.1 | 3.3 | cc, a | 980.5 | 9.7 | Leuchtenberger et al. 1956 |
| Primary spermatocyte (m) | 59.3 | 3.3 | cc, a | 1593.2 | 9.7 | Leuchtenberger et al. 1956 |
| Primary spermatocyte (m) | 42.1 | 3.9 | cc, a | 1275.2 | 11.3 | Leuchtenberger et al. 1956 |
| Primary spermatocyte (m) | 69.4 | 4.6 | cc, a | 1764.7 | 13.3 | Leuchtenberger et al. 1956 |
| Primary spermatocyte (m) | 45.1 | 4.6 | cc, a | 1333.5 | 13.4 | Leuchtenberger et al. 1956 |
| Primary spermatocyte (m) | 48.6 | 5.1 | cc, a | 1399.9 | 14.7 | Leuchtenberger et al. 1956 |
| Primary spermatocyte (m) | 48.2 | 5.4 | cc, a | 1392.4 | 15.8 | Leuchtenberger et al. 1956 |
| Secondary spermatocyte (m) | 14.2 | 1.5 | cc, a | 629.2 | 4.2 | Leuchtenberger et al. 1956 |
| Secondary spermatocyte (m) | 13.1 | 1.9 | cc, a | 597.0 | 5.4 | Leuchtenberger et al. 1956 |
| Secondary spermatocyte (m) | 17.6 | 1.9 | cc, a | 723.4 | 5.5 | Leuchtenberger et al. 1956 |
| Secondary spermatocyte (m) | 19.9 | 2.3 | cc, a | 783.5 | 6.8 | Leuchtenberger et al. 1956 |
| Secondary spermatocyte (m) | 33.4 | 2.6 | cc, a | 1097.0 | 7.7 | Leuchtenberger et al. 1956 |
| Secondary spermatocyte (m) | 25.9 | 2.7 | cc, a | 929.9 | 8.0 | Leuchtenberger et al. 1956 |
| Secondary spermatocyte (m) | 20.6 | 2.9 | cc, a | 801.3 | 8.4 | Leuchtenberger et al. 1956 |
| Secondary spermatocyte (m) | 26.2 | 3.0 | cc, a | 936.9 | 8.7 | Leuchtenberger et al. 1956 |
| Spermatid (m) | 5.2 | 0.6 | cc, a | 327.5 | 1.8 | Leuchtenberger et al. 1956 |
| Spermatid (m) | 8.7 | 1.0 | cc, a | 457.6 | 2.9 | Leuchtenberger et al. 1956 |
| Spermatid (m) | 5.3 | 1.0 | cc, a | 331.6 | 3.0 | Leuchtenberger et al. 1956 |
| Spermatid (m) | 8.0 | 1.1 | cc, a | 433.3 | 3.2 | Leuchtenberger et al. 1956 |
| Spermatid (m) | 8.7 | 1.4 | cc, a | 457.6 | 4.0 | Leuchtenberger et al. 1956 |
| Spermatid (m) | 9.0 | 1.5 | cc, a | 467.8 | 4.3 | Leuchtenberger et al. 1956 |
| Spermatid (m) | 9.5 | 1.5 | cc, a | 484.5 | 4.4 | Leuchtenberger et al. 1956 |
| Spermatid (m) | 6.5 | 1.5 | cc, a | 378.6 | 4.5 | Leuchtenberger et al. 1956 |
| Spermatogonium (m) | 39.3 | 1.9 | cc, a | 1219.4 | 5.6 | Leuchtenberger et al. 1956 |
| Spermatogonium (m) | 23.4 | 2.3 | cc, a | 870.5 | 6.7 | Leuchtenberger et al. 1956 |
| Spermatogonium (m) | 19.7 | 2.6 | cc, a | 778.4 | 7.4 | Leuchtenberger et al. 1956 |
| Spermatogonium (m) | 38.6 | 2.8 | cc, a | 1205.2 | 8.1 | Leuchtenberger et al. 1956 |
| Spermatogonium (m) | 51.1 | 3.4 | cc, a | 1446.3 | 10.0 | Leuchtenberger et al. 1956 |
| Spermatogonium (m) | 26.7 | 3.6 | cc, a | 948.4 | 10.5 | Leuchtenberger et al. 1956 |
| Spermatogonium (m) | 35.9 | 3.6 | cc, a | 1149.7 | 10.5 | Leuchtenberger et al. 1956 |
| Spermatogonium (m) | 51.9 | 3.8 | cc, a | 1461.0 | 11.0 | Leuchtenberger et al. 1956 |
| Spermatozoon (m) | 11.7 | 6.4 | c, a | 404.5 | 3.1 | Royere et al. 1988 |
| Spermatozoon (m) | 11.9 | 6.7 | cc, a | 410.9 | 3.3 | Royere et al. 1988 |
| Spermatozoon (m) | 11.1 | 6.7 | cc, a | 384.9 | 3.3 | Royere et al. 1988 |
| Spermatozoon (m) | 11.0 | 7.0 | cc, a | 380.5 | 3.4 | Royere et al. 1988 |
| Spermatozoon (m) | 11.6 | 7.0 | cc, a | 400.8 | 3.5 | Royere et al. 1988 |
| Spermatozoon (m) | 12.0 | 7.3 | cc, a | 414.2 | 3.6 | Royere et al. 1988 |
| Spermatozoon (m) | 11.5 | 7.4 | cc, a | 398.4 | 3.6 | Royere et al. 1988 |
| Spermatozoon (m) | 11.4 | 7.5 | cc, a | 394.0 | 3.7 | Royere et al. 1988 |
| Spermatozoon (m) | 13.0 | 7.7 | cc, a | 447.9 | 3.8 | Royere et al. 1988 |
| Spermatozoon (m) | 11.7 | 7.9 | cc, a | 405.1 | 3.9 | Royere et al. 1988 |
| Syncytiotrophoblast (m) | 81.0 | 1.8 | cc, p | 769.0 | 6.4 | Galton 1962 |
| Syncytiotrophoblast (m) | 72.0 | 1.9 | cc, p | 712.3 | 6.7 | Galton 1962 |
| Syncytiotrophoblast (m) | 79.0 | 2.2 | cc, p | 756.6 | 7.7 | Galton 1962 |
| Syncytiotrophoblast (m) | 77.0 | 2.2 | cc, p | 744.1 | 7.8 | Galton 1962 |
| Villous stroma (m) | 82.0 | 2.1 | cc, p | 775.2 | 7.4 | Galton 1962 |
| Villous stroma (m) | 108.0 | 2.1 | cc, p | 927.1 | 7.5 | Galton 1962 |
| Villous stroma (m) | 96.0 | 2.4 | cc, p | 858.8 | 8.5 | Galton 1962 |
| Villous stroma (m) | 102.0 | 2.5 | cc, p | 893.3 | 8.7 | Galton 1962 |
Data from 19 cell types used in analyses shown in Figures 1 and 2. The original (i.e., reported) values for cell/nuclear size and DNA content are listed in columns 2 and 3, and the original units in which these values were expressed are listed in column 4. For analyses, all of the measures of cell/nuclear size were converted to units of cell volume (μ3) shown in column 5, and measures of DNA content were converted to picograms of DNA shown in column 6. Letters in parentheses following the listing of cell type in column 1 denote whether the value is a measurement of a single cell (s) or the mean of a population of cells (m). The first notation used in column 4 indicates whether cell/nuclear size measurements were originally reported as cell diameter (d), nuclear cross-sectional area in calibrated arbitrary units (c), nuclear cross-sectional area in μ2 (cc), nuclear diameter in μ (n), or cell volume in μ3 (v). The second notation in column 4 indicates whether DNA content measurements were reported in units of ploidy level (p), arbitrary absorbance units (a), or picograms of DNA (pg). Cell types are reported based on cell-type designations given in original studies.
Computation of mean cell volumes: Studies reported cell or nuclear size using one of four measurements: cell volume, cell diameter/radius, nuclear cross-sectional area, or nuclear diameter/radius. Measurements of cell diameter/radius were converted to cell volume assuming cells were spherical. Measurements of nuclear cross-sectional area and diameter/radius were converted to nuclear volume assuming nuclei were spherical and that nuclear cross-sectional areas were circular. All estimates of nuclear volume were then converted to cell volume using a previously reported relationship between cell and nuclear volume of human cells (Swanson et al. 1991): cell volume = 44.2 (nuclear volume)0.65 as indicated in the text. In one case (Klinger and Schwarzacher 1960), measurements of nuclear area were given in calibrated arbitrary units. In this case, we converted back from arbitrary units to units of squared micrometers before computing nuclear radius (in micrometers).
Computation of mean DNA content: DNA content measurements were originally reported in one of three ways: as picograms of DNA, as ploidy level, or as arbitrary absorbance units of DNA. To convert ploidy level to pg DNA, we multiplied by the typical haploid DNA content of human cells (3.5 pg [Gregory 2012]). To convert arbitrary units to pg DNA, we determined the mean arbitrary unit value of cells that the original investigators of each study designated as diploid, and then assumed this corresponded to 2 × 3.5 = 7 pg of DNA to convert values from arbitrary units to pg DNA. Thus, each of the seven studies in which this conversion was performed had a unique conversion factor: Bedi and Goldstein 1976 (2.75 arbitrary units/pg DNA), Klinger and Schwarzacher 1960 (6.9 arbitrary units/pg DNA), Leuchtenberger et al. 1956 (0.34 arbitrary units/pg DNA), Meek and Harbison 1967 (2.1 arbitrary units/pg DNA), Petrakis 1953 (0.66 arbitrary units/pg DNA), Royere et al. 1988 (2.03 arbitrary units/pg DNA), and Swartz 1956 (0.37 pg). This conversion is possible because the Feulgen staining method results in a linear relationship between light absorbance and DNA content as discussed in the text.
Averaging individal cell measurements: For cases in which individual cell measurements were reported, we averaged all cell volume and DNA content measurements to yield a single population mean for each cell type within each study. Mean cell volumes of these cell types were 1574 µ3 (amnion epithelial cells [Klinger and Schwarzacher 1960]), 2936 µ3 (hepatocytes [Meek and Harbison 1967]), 1441 µ3 (lymphocytes [Petrakis 1953]), 764 µ3 (lymphocytes [Bedi and Goldstein 1976]), 817 µ3 (lymphocyte polymorphs [Bedi and Goldstein 1976]), and 1051 µ3 (monocytes [Bedi and Goldstein 1976]). Corresponding mean DNA contents were 12, 19.9, 7.1, 6.8, 6.7, and 7.3 pg, respectively. These means were used in the analyses presented in the text.