Fig. 17.

Ionic mechanism of histaminergic inhibitory postsynaptic potentials (ipsps) in aplysia. Paired recording in the histaminergic C2 neuron from aplysia and a follower neuron. Five action potentials are elicited (A) and the response is registered at different voltage levels (B, from −50 to −90 mV). Histamine is also puffed on the follower neuron at these different voltage levels (C). A fast component reverses at the equilibrium potential for Cl⁻, between −60 and −70 mV, a slow component near −90 mV, close to the K⁺-equilibrium potential. Modified from McCaman and Weinreich (1985).