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Overall 7TM X-ray structure of the H1 receptor (PDB ID 3RZE) bound with the tricyclic H1 receptor inverse agonist doxepin and a phosphate ion and a close-up on the binding site with residues surrounding doxepin and the phosphate ion. Residues are numbered as found in the human H1 receptor sequence and with the corresponding Ballesteros-Weinstein numbering.
