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. 2015 Jul;146(1):65–77. doi: 10.1085/jgp.201411336

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© 2015 Badheka et al.

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Figure 8. — Activation of PLCβ by carbachol inhibits mTRPM3α2 currents. (A) Representative whole-cell patch clamp experiment in a HEK cell expressing mTRPM3α2 and hM1 in the presence of 2 mM extracellular Ca²⁺. The applications of 50 µM PregS and 100 µM carbachol are indicated by the horizontal lines. (B) Summary of data normalized to the peak of the PregS-induced current at the time points indicated. Error bars represent SEM.