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. 2015 Jul;146(1):79–96. doi: 10.1085/jgp.201511380

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© 2015 Karlin

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Figure 3. — Simulation of the effects of inhibiting BK. (A) V_exp and (B) Ca_exp (red circles with error bars) were recorded at 60 mm Hg in the presence of 100 nM iberiotoxin (Knot et al., 1998). V_m and Ca_in were simulated with the number of BK molecules (BK_T) set at the indicated multiples (1–120%) of its normal value. <V_m> and <Ca_in> are the means over the last 50 s of a 300-s simulation (black symbols). Except for BK_T, the parameters were normal. Error bars represent standard deviations of the experimental data.