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. 2015 Jul;146(1):79–96. doi: 10.1085/jgp.201511380

Figure 4.

Figure 4.

Simulation of the effects of inhibiting RyR. (A) Vexp and (B) Caexp (red circles with error bars) were recorded at 60 mm Hg in the presence of 10 µM ryanodine (Knot et al., 1998). Vm and Cain were simulated with RyRT set at the indicated multiples (1–120%) of its normal value. <Vm> and <Cain> are the means over the last 50 s of a 300-s simulation (black symbols). Except for RyRT, the parameters were normal. Error bars represent standard deviations of the experimental data.