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. 2015 Jul;146(1):79–96. doi: 10.1085/jgp.201511380

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© 2015 Karlin

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Figure 5. — Simulation of the effects of inhibiting CaV channels. (A) V_exp and (B) Ca_exp (red circles with error bars) were recorded at various intravascular pressures in the presence of 10 nM nisoldipine (Knot and Nelson, 1998). V_m and Ca_in were simulated with CaV_T set at the indicated multiples (1–120%) of its normal value. <V_m> and <Ca_in> are the means over the last 50 s of a 300-s simulation (black symbols). Except for CaV_T, the parameters were normal. Error bars represent standard deviations of the experimental data.