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. 2015 Jul;146(1):79–96. doi: 10.1085/jgp.201511380

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© 2015 Karlin

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Figure 8. — Effects of intravascular pressure and vasorelaxants on <V_m> and <Ca_in> in the absence of BK β1. (A) <V_m> and (B) <Ca_in> were computed as before either with normal parameters (closed red circles), which include those appropriate for the BK channel containing both α and β1 subunits (+BKβ1) (Bao and Cox, 2005), or with parameters appropriate for BK α alone (−BKβ1) (Horrigan and Aldrich, 2002), in the absence (open red circles) or presence (open black symbols) of effectors. 0.1 µM βA (open black triangles), 0.4 µM NO (open black squares), or 0.2 µM EET (open black diamonds) was added steadily from t = 40–300 s.