Fig. 3.

L. lactis I-1631 reduces primary CEC superoxide levels in vivo and in vitro. (A) Superoxide levels in CECs isolated from T-bet^−/− Rag2^−/− mice and stained with DHE. T-bet^−/− Rag2^−/− mice were treated as labeled. Box and whiskers plot; data reflect samples from four experiments; unpaired t test. (B) Superoxide levels in CECs isolated from wild-type mice and stained with DHE. Cells were stimulated with xanthine and xanthine oxidase or unstimulated. Additional treatment with L. lactis I-1631 or L. lactis ΔsodA culture lysates is as labeled. Box and whiskers plot; data reflect six experiments. One-way ANOVA with post hoc Bonferroni’s MCT. *P < 0.05 and **P < 0.01.