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Binding of RH189 (AMG+exon4) to HAP was greater than that of RH175 (AMG). Proteins were incubated with HAP for up to 60 min, and the amount of protein absorbed onto the HAP was determined at 10-minute intervals. At all time-points, the binding of RH189 to HAP was calculated to be significantly greater (*P < 0.001).
