Table 2.
Distribution frequency of normal/CIN1, CIN2, and CIN3 + lesions by method of biopsy, grouped by cervical quadrant location
| Quadrants | Diagnosis | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Normal/CIN1 | CIN2 | CIN3+ | Total | ||||||||||||
| n | n/Nr(%) | 95%CI | n | n/Nr(%) | 95%CI | n | n/Nr(%) | 95%CI | Nr | Nr/N(%) | |||||
| Directed biopsy | |||||||||||||||
| Q1 | 1968 | 88.1 | 86.7 | 89.4 | 129 | 5.8 | 4.9 | 6.8 | 136 | 6.1 | 5.2 | 7.1 | 2233 | 4.2 | |
| Q2 | 1583 | 83.2 | 81.5 | 84.8 | 167 | 8.8 | 7.6 | 10.1 | 153 | 8.0 | 6.9 | 9.3 | 1903 | 3.6 | |
| Q3 | 1548 | 82.8 | 81.1 | 84.5 | 146 | 7.8 | 6.7 | 9.1 | 175 | 9.4 | 8.1 | 10.8 | 1869 | 3.5 | |
| Q4 | 2238 | 88.4 | 87.1 | 90.0 | 126 | 5.0 | 4.2 | 5.9 | 169 | 6.7 | 5.7 | 7.7 | 2533 | 4.8 | |
| P < 0.0001 | |||||||||||||||
| Random biopsy | |||||||||||||||
| Q1 | 8698 | 98.2 | 97.9 | 98.5 | 87 | 1.0 | 0.8 | 1.2 | 72 | 0.8 | 0.6 | 1.0 | 8857 | 16.7 | |
| Q2 | 8873 | 97.9 | 97.6 | 98.2 | 106 | 1.2 | 1.0 | 1.4 | 80 | 0.9 | 0.7 | 1.1 | 9059 | 17.1 | |
| Q3 | 8717 | 97.8 | 97.5 | 98.1 | 118 | 1.3 | 1.1 | 1.6 | 77 | 0.9 | 0.7 | 1.1 | 8912 | 16.8 | |
| Q4 | 8521 | 98.2 | 97.9 | 98.4 | 94 | 1.1 | 0.9 | 1.3 | 65 | 0.7 | 0.6 | 0.9 | 8680 | 16.4 | |
| P = 0.1911 | |||||||||||||||
| ECC | |||||||||||||||
| 8766 | 96.9 | 96.6 | 97.3 | 101 | 1.1 | 0.9 | 1.4 | 175 | 1.9 | 1.7 | 2.2 | 9042 | 17.0 | ||
| Total | 50912 | 95.9 | 95.7 | 96.1 | 1074 | 2.0 | 1.9 | 2.1 | 1102 | 2.1 | 2.0 | 2.2 | 53088 | 100.0 | |
CIN cervical intraepithelial neoplasia; Q quadrant; ECC endocervical curettage; CI confidence interval