Bone marrow-derived macrophages derived from wild-type mice (WT), but not
Ager
null mice, induce
Tnfa
mRNA expression in response to 0.3 μM
IsoLG-PE. Results are shown as mean±SEM of all replicates on 2 separate days, n=6 replicates per day, with each replicate representing cells derived from independent femur, and normalized to expression in wild-type control-treated cells. One-way ANOVA p<0.0001, Bonferroni's multiple-comparison test *p<0.05 versus WT control-treated cells, #p<0.05 for WT cells treated with IsoLG-PE versus Ager null treated with IsoLG-PE.