Table 3.
Changes in Secondary Outcome Measures
| Variable | Pre | Post | Patients (n) | p-Value | Change (95% confidence interval) |
|---|---|---|---|---|---|
| EQ-5D-5L | 0.60±.16 | 0.68±.15 | 23 | 0.002a | 0.08 (0.03 to 0.1) |
| SF-12, PCS | 28.1±7.5 | 33.6±10.5 | 13b | 0.002a | 5.5 (2.4 to 8.6) |
| SF-12, MCS | 43.7±18.3 | 50.7±14.9 | 6b | 0.080c | 7.0 (−1.2 to 15.3) |
| PROMIS-PI | 20.1±5.0 | 17.0±5.9 | 23 | 0.005a | −3.2 (−5.3 to −1.1) |
| Knee range of motion (degrees) | 113.9±13.0 | 117.5±15.0 | 23 | 0.087 | 3.6 (−0.6 to 7.8) |
| 50-ft walk (sec) | 13.5±2.2 | 12.8±2.4 | 23 | 0.121 | −0.7 (−1.7 to 0.2) |
Values expressed with a plus/minus sign are the mean±standard deviation. Negative values for mean paired difference for PROMIS Pain Interference and time to walk 50 feet indicate improvement on these measures.
a
Significant at p<0.05.
b
Standard scoring of the SF-12 specifies that participants with any missing data be dropped from the analysis.
c
Trend in expected direction at p<0.10.
EQ-5D-5L, the EuroQol health status index; SF-21, 12-Item Short-Form Health Survey; MCS, Mental Composite Score; PCS, Physical Composite Score; PROMIS-PI, Patient Reported Outcomes Measurement Information System-Pain Interference.