Table 1.

Characteristics and blood parameters of mice fed a CD or a HFD. Data are expressed as means±s.e.m. (n=6–8)

	CD	HFD
Initial body weight (g)	23.9±0.6	24.2±0.6
Final body weight (g)	30.2±0.4	49.6±0.9‡
Epididymal fat weight (g)	0.54±0.01	2.59±0.24‡
24-h food intake (g)	3.27±0.07	2.62±0.04‡
24-h energy intake (kJ)	46.5±1.0	57.4±0.8‡
Blood glucose (mmol/l)	6.5±0.3	9.8±0.7*
Plasma insulin (ng/ml)	0.35±0.01	1.65±0.09‡
Plasma leptin (ng/ml)	6.1±0.4	89.1±5.6‡
Plasma ghrelin (fmol/ml)	65.7±9.9	8.8±1.2†
Plasma des-acyl ghrelin (fmol/ml)	1255±157	937±54*

*P<0.05, ^† P<0.01, and ^‡ P<0.001 versus CD.