. Author manuscript; available in PMC: 2016 Jul 1.

Published in final edited form as: Am J Kidney Dis. 2015 Mar 17;66(1):114–124. doi: 10.1053/j.ajkd.2015.01.019

Table 4.

Changes in kidney function over time.

Measurement	Follow-up Duration (mo)	Group	Rate of Change in Kidney Function	P
mGFR (mL/min per y)	12–36	Controls	−0.36±7.55 (194)	0.005
	12–36	Donors	1.47±5.02 (198)	0.005
	36	Controls	−0.19±5.31 (172)	0.002
	36	Donors	1.30±3.49 (181)	0.002
mGFR (mL/min/1.73 m² per y)	12–36	Controls	−0.44±7.35 (194)	0.01
	12–36	Donors	1.09±4.28 (198)	0.01
	36	Controls	−0.39±4.81 (172)	0.004
	36	Donors	0.84±3.09 (181)	0.004
eGFR_cr (mL/min/1.73 m² per y)	12–36	Controls	−1.04±6.16 (196)	<0.001
	12–36	Donors	1.82±4.92 (200)	<0.001
	36	Controls	−0.46±3.68 (173)	<0.001
	36	Donors	1.60±3.75 (182)	<0.001
eGFR_cys (mL/min/1.73 m² per y)	12–36	Controls	−0.33±7.36 (196)	0.003
	12–36	Donors	1.82±6.76 (200)	0.003
	36	Controls	0.16±4.68 (173)	0.04
	36	Donors	1.21±5.06 (182)	0.04
eGFR_cr-cys (mL/min/1.73 m² per y)	12–36	Controls	−0.73±6.38 (196)	<0.001
	12–36	Donors	1.89±4.58 (200)	<0.001
	36	Controls	−0.07±3.85 (173)	<0.001
	36	Donors	1.49±3.81 (182)	<0.001

Note: Unless otherwise indicated, changes in kidney function over time (“slopes”).are given as mean ± standard deviation (number sampled). Shown are slopes with and without dropping cases that did not have a 36 month visit.

Abbreviations and definitions: CysC, cystatin C; eGFR_cr, estimated glomerular filtration rate calculated by Chronic Kidney Disease Epidemiology Collaboration creatinine equation; eGFR_cr-cys, estimated glomerular filtration rate calculated by Chronic Kidney Disease Epidemiology Collaboration creatinine-cystatin C equation; eGFR_cys, estimated glomerular filtration rate calculated by Chronic Kidney Disease Epidemiology Collaboration cystatin C equation; mGFR, glomerular filtration rate measured by iohexol plasma clearance.

T-test.