Table 3.
Multivariate regression analysis of predictors of outcome on Likert scale (excluding resolution) (column A) and resolution (column B) of any mood disorder regardless of attribution.
| Predictors | A: Analysis of Likert scale outcome (excluding resolution) | B: Analysis of time to resolution | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Est. | 95% CI | P | HR | 95% CI | P | ||||
| Gender | Female | 0.20 | −0.26 | 0.66 | 0.3985 | ||||
| Age at SLE diagnosis | 0.805 | 0.637 | 1.019 | 0.0711 | |||||
| Location | US | −0.39 | −1.64 | 0.85 | 0.0003 | 0.565 | 0.211 | 1.518 | 0.0125 |
| Mexico | 0.52 | −0.82 | 1.85 | 0.793 | 0.288 | 2.187 | |||
| Europe | 0.73 | −0.55 | 2.01 | 0.551 | 0.203 | 1.496 | |||
| Canada | 0.33 | −0.95 | 1.62 | 1.160 | 0.438 | 3.078 | |||
| Asia | 0 | 1 | |||||||
| Anti-depressant | 0.51 | 0.12 | 0.90 | 0.0096 | |||||
| Immunosuppressive | 0.55 | 0.20 | 0.91 | 0.0031 | |||||
| Any ongoing NP events in central/peripheral clusters by attribution* | Central, SLE attributed | −0.39 | −0.83 | 0.04 | 0.0294 | 0.693 | 0.424 | 1.133 | 0.0183 |
| Central, non-SLE attributed | −0.52 | −0.93 | −0.12 | 0.595 | 0.394 | 0.898 | |||
| Peripheral, SLE attributed | 0.26 | −0.94 | 1.46 | 1.540 | 0.728 | 3.258 | |||
| Peripheral, non-SLE attributed | −1.01 | −2.02 | −0.01 | Not estimable | |||||
| No NP events | 0 | 1 | |||||||
| Time since mood disorder onset | 5+ years | −0.30 | −0.74 | 0.14 | 0.3168 | ||||
| 4–5 years | 0.05 | −0.40 | 0.50 | ||||||
| 2–3 years | 0.10 | −0.26 | 0.45 | ||||||
| <=1 year | 0 | 0 | 0 | ||||||
Central, SLE attributed: patients with one or more ongoing central SLE attributed events at current visit
Central, non-SLE attributed: patients with one or more ongoing central non-SLE attributed events, but no ongoing central SLE-attributed events
Peripheral, SLE attributed: Patients with ongoing peripheral events only, of which one or more were SLE-attributed
Peripheral, non-SLE attributed: Patients with ongoing peripheral non-SLE attributed events only
No NP: patients without any ongoing NP events at current visit