Table 1.
Definition of Cataract and Number of Participants and Eyes in Analyses
| A. Definition of controls and cataract types evaluated in the Age-Related Eye Disease Study (AREDS) | |||
|---|---|---|---|
| Cataract type | Mild | Moderate | Controls |
| Nuclear | AREDS nuclear grade >2 and ≤4 | AREDS nuclear grade ≥4 | AREDS nuclear grade ≤2 |
| Cortical | Cortical >0% and <10% | Cortical ≥10% | Cortical = 0% |
| Posterior Subcapsular (PSC) | PSC >0% and <5% | PSC ≥5% | PSC = 0% |
| 1B. Numbers of participants and eyes included in the prevalence analyses of the lutein/zeaxanthin and vitamin B and cataracts analyses | ||||||
|---|---|---|---|---|---|---|
| Nuclear | Cortical | |||||
| N participants | N eyes | N (%) eyes with event | N eyes | N participants | N (%) eyes with event | |
| Mild | 2939 | 5582 | 2279 (40.8) | 2788 | 5296 | 3294 (62.2) |
| Moderate | 2358 | 3840 | 537 (14.0) | 1852 | 2618 | 616 (23.5) |
| 1C. Numbers of participants and eyes included in the incidence analyses of the lutein/zeaxanthin and vitamin B and cataracts analyses | |||||||
|---|---|---|---|---|---|---|---|
| Centrum=No | Centrum=Yes | ||||||
| Opacity | N participants | N eyes | N (%) eyes with event | N eyes | N participants | N (%) eyes with event | |
| Mild | Nuclear | 639 | 1045 | 734 (70.2) | 1190 | 1963 | 1279 (65.2) |
| Cortical | 470 | 658 | 312 (47.4) | 903 | 1245 | 619 (49.7) | |
| PSC | 939 | 1727 | 185 (10.7) | 1807 | 3315 | 347 (10.5) | |
| Moderate | Nuclear | 505 | 674 | 326 (48.4) | 966 | 1354 | 617 (45.6) |
| Cortical | 583 | 825 | 293 (35.5) | 1132 | 1597 | 590 (36.9) | |
| PSC | 951 | 1716 | 161 (9.4) | 1842 | 3326 | 313 (9.4) | |
| Cat surgery | 1043 | 2047 | 558 (27.3) | 2025 | 3985 | 1009 (25.3) | |