Table 1.
Demographic Information
Minocycline (N=28) | Placebo (N=23) | |
---|---|---|
Age (years) | 42.9 ± 14.2 | 42.3 ± 11.0 |
Race | 18 White (64%) 8 Black (29%) |
13 White (57%) 8 Black (35%) |
Sex (male) | 20 (71%) | 18 (78%) |
Age of Illness Onset | 18.5 ± 6.2 | 19.3 ± 5.7 |
Level of Education | 12.1 ± 1.6 | 12.2 ± 2.6 |
Inpatients | 11 (39%) | 7 (30%) |
Clozapine dose (mg/day) | 423.1 ± 189.5 | 433.7 ± 140.1 |
Total Clozapine level (ng/mL) | 777.4 ± 392.8 | 816.6 ± 339.5 |
Clozapine (ng/mL) | 489.5 ± 257.1 | 517.7 ± 211.2 |
Norclozapine (ng/mL) | 287.9 ± 165.0 | 298.9 ± 172.6 |
Other Antipsychotic | 13 (46%) | 8 (35%) |
First Generation | 4 (14%) | 1 (4%) |
Second Generation | 9 (32%) | 7 (30%) |
Antidepressant | 14 (50%) | 8 (35%) |
Mood Stabilizer | 10 (36%) | 6 (26%) |
Anticholinergic | 4 (14%) | 3 (13%) |
Benzodiazepine | 15 (54%) | 9 (39%) |